Evidence map›Paper›PMID 27291327›Full record

Trial reportInternational journal of clinical practice2016

Telemonitoring in heart failure patients treated by cardiac resynchronisation therapy with defibrillator (CRT-D): the TELECART Study.

C Sardu, M Santamaria, M R Rizzo, M Barbieri, M di Marino, G Paolisso, G Santulli, R Marfella

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of clinical practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  18. [Telemedicine in chronic heart failure].Innere Medizin (Heidelberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C SarduDepartment of Arrhythmias and Electrophysiology, 'John Paul II' Research and Care Foundation, Campobasso, Italy.
M SantamariaDepartment of Arrhythmias and Electrophysiology, 'John Paul II' Research and Care Foundation, Campobasso, Italy.
M R RizzoDepartment of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, Naples, Italy.
M BarbieriDepartment of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, Naples, Italy.
M di MarinoDepartment of Arrhythmias and Electrophysiology, 'John Paul II' Research and Care Foundation, Campobasso, Italy.
G PaolissoDepartment of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, Naples, Italy.
G SantulliColumbia University Medical Center, New York, NY, USA.
R MarfellaDepartment of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, Naples, Italy.

Funding

Targeting intracellular calcium leak as novel therapy for diabetesK99DK107895 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SANTULLI, GAETANO · 2015 to 2016
$176k
NIDDK NIH HHS K99 DK107895
6 · The paper itself

Abstract

aimTelemonitoring (TM) is a safe and efficient monitoring system for internal cardioverter defibrillator device (ICD) recipients. TM has been used to track info on the clinical status of heart failure patients treated by ICD and/or cardiac resynchronisation therapy defibrillator (CRT-D). The aim of this study was to investigate the impact of TM on clinical outcomes in a population of CRT-D patients with heart failure.

methodsIn a multicentre, randomised study, patients with chronic heart failure, New York Heart Association (NYHA) functional class II or III, left bundle branch block, severe left ventricle ejection fraction reduction (LVEF < 35%) have been identified and screened.

resultsOne hundred and ninety-one patients have been randomised to receive either a CRT-D with TM or a CRT-D with traditional ambulatory monitoring (control group) and completed the 12-month study follow-up. Primary endpoints were all cause death, cardiac death and hospital admission for heart failure. Secondary endpoints were atrial fibrillation, sustained episodes, non-sustained and self terminated ventricular tachyarrhythmia, sustained ventricular tachycardia, and ventricular fibrillation, ICD shocks and percentage of CRT-D responder patients. Univariate analysis identified the following factors predicting hospitalisation: TM, age, chronic kidney disease, hypercholesterolaemia, LVEF and NYHA class. At multivariate analysis, TM was the only factor predicting heart failure hospitalisation (hazard ratio 0.6, 0.42-0.79, 95% CI, p = 0.002), without affecting overall mortality and cardiac deaths events.

conclusionsTaken together, our data indicate the importance of TM in predicting heart failure hospitalisation in patients treated with CRT-D.

Indexed as

Cardiac Resynchronization TherapyAgedDefibrillators, ImplantableFemaleHeart FailureHospitalizationHumansMaleMonitoring, AmbulatoryTelemetry

Identifiers

PMID27291327
PMCPMC5813682

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.