ArticlePflugers Archiv : European journal of physiology2016
Estimation of the flow resistances exerted in coronary arteries using a vessel length-based method.
Article in Pflugers Archiv : European journal of physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Performance of a Novel CT-Derived Fractional Flow Reserve Measurement to Detect Hemodynamically Significant Coronary Stenosis.Journal of Korean medical science · 2023Article
- A Simple Method for Automatic 3D Reconstruction of Coronary Arteries From X-Ray Angiography.Frontiers in physiology · 2021Article
- Article
- Prediction of Plaque Progression in Coronary Arteries Based on a Novel Hemodynamic Index Calculated From Virtual Stenosis Method.Frontiers in physiology · 2019Article
- A vessel length-based method to compute coronary fractional flow reserve from optical coherence tomography images.Biomedical engineering online · 2017Article
- Physiome approach for the analysis of vascular flow reserve in the heart and brain.Pflugers Archiv : European journal of physiology · 2017Review
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Authors and funding
7 authors at 4 institutions in 1 country.
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Abstract
Flow resistances exerted in the coronary arteries are the key parameters for the image-based computer simulation of coronary hemodynamics. The resistances depend on the anatomical characteristics of the coronary system. A simple and reliable estimation of the resistances is a compulsory procedure to compute the fractional flow reserve (FFR) of stenosed coronary arteries, an important clinical index of coronary artery disease. The cardiac muscle volume reconstructed from computed tomography (CT) images has been used to assess the resistance of the feeding coronary artery (muscle volume-based method). In this study, we estimate the flow resistances exerted in coronary arteries by using a novel method. Based on a physiological observation that longer coronary arteries have more daughter branches feeding a larger mass of cardiac muscle, the method measures the vessel lengths from coronary angiogram or CT images (vessel length-based method) and predicts the coronary flow resistances. The underlying equations are derived from the physiological relation among flow rate, resistance, and vessel length. To validate the present estimation method, we calculate the coronary flow division over coronary major arteries for 50 patients using the vessel length-based method as well as the muscle volume-based one. These results are compared with the direct measurements in a clinical study. Further proving the usefulness of the present method, we compute the coronary FFR from the images of optical coherence tomography.
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