Evidence map›Paper›PMID 27288651›Full record

ReviewCurrent opinion in immunology2016

Challenges and strategies for the eradication of the HIV reservoir.

Jason T Kimata, Andrew P Rice, Jin Wang

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. P-TEFb as A Promising Therapeutic Target.Molecules (Basel, Switzerland) · 2020
    Review
  14. Article
  15. Review
  16. Article
  17. Pharmacokinetic stability of macrocyclic peptide triazole HIV-1 inactivators alone and in liposomes.Journal of peptide science : an official publication of the European Peptide Society · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jason T KimataDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States. Electronic address: jkimata@bcm.edu.
Andrew P RiceDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, United States.
Jin WangDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, TX, United States.
Baylor College of Medicine · US

Funding

Virology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BUTEL, JANET S · 1994 to 2015
$21.7M
Molecular Regulation of Long-term Immune MemoryR01AI123221 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WANG, JIN · 2016 to 2020
$2.0M
MOLECULAR REGULATION OF IMMUNITY TO VIRAL INFECTIONSR01AI116644 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WANG, JIN · 2016 to 2020
$2.0M
Inhibition of HIV by GPI-anchored Antibody DerivativesR01AI106574 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI KIMATA, JASON T. · 2013 to 2015
$600k
Role of P-TEFB in HIV latencyR21AI116173 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI RICE, ANDREW P · 2014 to 2015
$435k
Mechanisms of Reactivation of Latent HIV by HDAC InhibitorsR21AI110263 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI RICE, ANDREW P · 2014 to 2015
$430k
NIAID NIH HHS P30 AI036211NIAID NIH HHS R01 AI106574NIAID NIH HHS R01 AI116644NIAID NIH HHS R01 AI123221NIAID NIH HHS R21 AI110263NIAID NIH HHS R21 AI116173
6 · The paper itself

Abstract

Despite the success of highly active antiretroviral therapy (HAART) for inhibiting HIV replication and improving clinical outcomes, it fails to cure infection due to the existence of a stable latent proviral reservoir in memory CD4

Indexed as

Virus LatencyAnimalsAntiretroviral Therapy, Highly ActiveCD4-Positive T-LymphocytesCombined Modality TherapyHIVHIV InfectionsHumansImmunotherapyViral LoadVirus Integration

Identifiers

PMID27288651
PMCPMC5086301
OpenAlexW2410601385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.