ArticleBMJ open2016
Following young people with perinatal HIV infection from adolescence into adulthood: the protocol for PHACS AMP Up, a prospective cohort study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02119702 (Adolescent Master Protocol for Participants 18 Years of Age and Older), which is not on this map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)
Who cites it
26 citing papers in PubMed, 34 citations in OpenAlex.
- Low SARS-CoV-2 Positivity in a Large, Diverse US-Based Study of Persons Affected by HIV.AIDS and behavior · 2026Article
- Effective Handling of Health Care Transition for Young People Living With HIV: A Consensus of Experts in Thailand Using Modified Delphi Method.The Journal of the Association of Nurses in AIDS Care : JANAC · 2026Article
- Longitudinal assessment of inflammatory biomarkers among youth with perinatal HIV infection and HIV exposure.AIDS (London, England) · 2026Article
- Executive Function and Adherence in Children and Adolescents Living With HIV: Evidence From the HIV-Associated Neurocognitive Disorders in Zambia (HANDZ) Study.Journal of child neurology · 2026Article
- Plasma Inflammatory Biomarkers Lack Strong Association With Cognitive Outcomes Among Young Adults With Perinatal HIV Exposure and/or Acquisition.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Long-Term Outcomes of Young Adults With Perinatal Human Immunodeficiency Virus (HIV) Infection in the United States and Puerto Rico.Open forum infectious diseases · 2025Article
- Group-wise normalization in differential abundance analysis of microbiome samples.BMC bioinformatics · 2025Article
- Birth outcomes following bictegravir exposure during pregnancy.AIDS (London, England) · 2025Article
- Article
- Relationship between brain structural network integrity and emotional symptoms in youth with perinatally-acquired HIV.Brain, behavior, and immunity · 2024Article
- Creating a data collection and management platform to support measurement of adolescent HIV care transition processes within low- and middle-income countries: The GRADUATE project.PLOS global public health · 2024Article
- Association of Perceived Social Support with Viral Suppression Among Young Adults with Perinatally-Acquired HIV in the US-based Pediatric HIV/AIDS Cohort Study (PHACS).Clinical epidemiology · 2023Article
- A case study and proposal for publishing directed acyclic graphs: The effectiveness of the quadrivalent human papillomavirus vaccine in perinatally HIV Infected girls.Journal of clinical epidemiology · 2022Article
- Central Nervous System Impact of Perinatally Acquired HIV in Adolescents and Adults: an Update.Current HIV/AIDS reports · 2022Review
- Inconsistent Sexual Behavior Reporting Among Youth Affected by Perinatal HIV Exposure in the United States.AIDS and behavior · 2021Article
- Ethical challenges of the healthcare transition to adult antiretroviral therapy (ART) clinics for adolescents and young people with HIV in Uganda.BMC medical ethics · 2021Article
- Barriers and facilitators for transitioning of young people from adolescent clinics to adult ART clinics in Uganda: unintended consequences of successful adolescent ART clinics.BMC health services research · 2020Article
- Bayesian variable selection for multivariate zero-inflated models: Application to microbiome count data.Biostatistics (Oxford, England) · 2020Article
- Healthcare Transition Outcomes Among Young Adults With Perinatally Acquired Human Immunodeficiency Virus Infection in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Using Social Media and Technology to Communicate in Pediatric HIV Research: Qualitative Study With Young Adults Living With or Exposed to Perinatal HIV.JMIR pediatrics and parenting · 2020Article
Corrections and comments
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Authors and funding
18 authors at 9 institutions in 1 country.
Funding
Abstract
introductionThe first generation of adolescents born with HIV infection has reached young adulthood due to advances in treatment. It is important to continue follow-up of these individuals to assess their long-term medical, behavioural and mental health and ability to successfully transition to adulthood while coping with a chronic, potentially stigmatising condition. To accomplish this, and to maintain their interest in long-term research participation, we need to accommodate the changing lifestyles and interests of young adult study participants while ensuring valid data collection. We report the protocol for Pediatric HIV/AIDS Cohort Study (PHACS) Adolescent Master Protocol (AMP) Up, a prospective cohort study enrolling young adult participants for long-term follow-up. METHODS AND ANALYSIS: AMP Up is recruiting 850 young men and women 18 years of age and older-600 perinatally HIV-infected and a comparison group of 250 perinatally HIV-exposed, uninfected-at 14 clinical research sites in the USA and Puerto Rico. Recruitment began in April 2014 and is ongoing, with 305 participants currently enrolled. Planned follow-up is ≥6 years. Data are collected with a flexible hybrid of online and in-person methods. Outcomes include: transition to adult clinical care and retention in care; end-organ diseases; malignancies; metabolic complications; sexually transmitted infections; reproductive health; mental health and neurocognitive functioning; adherence to antiretroviral treatment; sexual behaviour and substance use; hearing and language impairments; and employment and educational achievement. ETHICS AND DISSEMINATION: The study received ethical approval from the Harvard T.H. Chan School of Public Health's institutional review board (IRB), and from the IRBs of each clinical research site. All participants provide written informed consent; for cognitively impaired individuals with legally authorised representatives, legal guardian permission and participant assent is obtained. Findings will be disseminated through peer-reviewed journals, conference presentations and participant summaries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.