ReviewAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2016
Systematic Molecular Phenotyping: A Path Toward Precision Emergency Medicine?
Review in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Precision acute medical care through "-omic" analyses: a scoping review.Personalized medicine · 2025Article
- The Role of Sex and Gender in Precision Emergency Medicine: A Scoping Review and Proposed Hierarchy.Clinical therapeutics · 2024Article
- Precision Emergency Medicine: A Systematic Review.Cureus · 2024Review
- 2023 Society for Academic Emergency Medicine Consensus Conference on Precision Emergency Medicine: Development of a policy-relevant, patient-centered research agenda.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024Article
- Characteristics of Emergency Medicine Specimen Bank Participants Compared to the Overall Emergency Department Population.The western journal of emergency medicine · 2023Article
- United States Emergency Department Use of Medications with Pharmacogenetic Recommendations.The western journal of emergency medicine · 2021Article
- Review
- Precision medicine: Uses and challenges.Medical journal, Armed Forces India · 2021Review
- Can miRNAs Be Considered as Diagnostic and Therapeutic Molecules in Ischemic Stroke Pathogenesis?-Current Status.International journal of molecular sciences · 2020Review
- Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites.Human genomics · 2020Article
- The Current Status of Genes and Genetic Testing in Emergency Medicine: A Narrative Review.Advanced journal of emergency medicine · 2020Review
- The Emergency Medicine Specimen Bank: An Innovative Approach To Biobanking In Acute Care.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Precision medicine is an emerging approach to disease treatment and prevention that considers variability in patient genes, environment, and lifestyle. However, little has been written about how such research impacts emergency care. Recent advances in analytical techniques have made it possible to characterize patients in a more comprehensive and sophisticated fashion at the molecular level, promising highly individualized diagnosis and treatment. Among these techniques are various systematic molecular phenotyping analyses (e.g., genomics, transcriptomics, proteomics, and metabolomics). Although a number of emergency physicians use such techniques in their research, widespread discussion of these approaches has been lacking in the emergency care literature and many emergency physicians may be unfamiliar with them. In this article, we briefly review the underpinnings of such studies, note how they already impact acute care, discuss areas in which they might soon be applied, and identify challenges in translation to the emergency department (ED). While such techniques hold much promise, it is unclear whether the obstacles to translating their findings to the ED will be overcome in the near future. Such obstacles include validation, cost, turnaround time, user interface, decision support, standardization, and adoption by end-users.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.