Evidence map›Paper›PMID 27287911›Full record

Trial reportSurgical endoscopy2017

Effect of morbid obesity, gastric banding and gastric bypass on esophageal symptoms, mucosa and function.

Jan Borovicka, Claudia Krieger-Grübel, Boudewijn van der Weg, Martin Thurnheer, Bernd Schultes, Michael Christian Sulz, Jean-Pierre Gutzwiler, Philipp Bisang, Daniel Pohl, Michael Fried and 2 more

Abstract readClinical TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Surgery-related gastrointestinal symptoms in a prospective study of bariatric surgery patients: 3-year follow-up.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017
    Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jan BorovickaDivision of Gastroenterology, Kantonsspital St. Gallen, 9001, St. Gallen, Switzerland.
Claudia Krieger-GrübelDivision of Gastroenterology, Kantonsspital St. Gallen, 9001, St. Gallen, Switzerland.
Boudewijn van der WegDivision of Gastroenterology, Kantonsspital St. Gallen, 9001, St. Gallen, Switzerland.
Martin ThurnheerHirslanden Clinic, 9016, St. Gallen, Switzerland.
Bernd SchultesHirslanden Clinic, 9016, St. Gallen, Switzerland.
Michael Christian SulzDivision of Gastroenterology, Kantonsspital St. Gallen, 9001, St. Gallen, Switzerland.
Jean-Pierre GutzwilerPrivate Gastroenterology Practice, 8800, Thalwil, Switzerland.
Philipp BisangHirslanden Clinic, 9016, St. Gallen, Switzerland.
Daniel PohlDivision of Gastroenterology, University Hospital Zurich, 8091, Zurich, Switzerland.
Michael FriedDivision of Gastroenterology, University Hospital Zurich, 8091, Zurich, Switzerland.
Christa MeyenbergerDivision of Gastroenterology, Kantonsspital St. Gallen, 9001, St. Gallen, Switzerland.
Radu TutuianDivision of Gastroenterology, University Hospital Zurich, 8091, Zurich, Switzerland. radu.tutuian@insel.ch.
Kantonsspital St. Gallen · CHKlinik Hirslanden · CHUniversity Hospital of Zurich · CHUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity and gastroesophageal reflux disease (GERD) are commonly associated diseases. Bariatric surgery has been shown to have various impacts on esophageal function and GERD. Our aim was to evaluate changes in symptoms, endoscopic findings, bolus passage and esophageal function in patients after primary gastric bypass surgery as compared to patients converted from gastric banding to gastric bypass.

methodsObese patients scheduled for laparoscopic Roux-en-Y gastric bypass (naïve-to-bypass) and patients who previously underwent gastric banding and were considered for conversion from gastric banding to gastric bypass (band-to-bypass) were included. Patients rated esophageal and epigastric symptoms (100 point VAS) and underwent upper endoscopy, impedance-manometry, and modified "timed barium swallow" before/after surgery.

resultsData from 66 naïve-to-bypass patients (51/66, 77 % females, mean age 41.2 ± 11.1 years) and 68 band-to-bypass patients (53/68, 78 % females, mean age 43.8 ± 10.0 years) were available for analysis. Esophageal symptoms, esophagitis, esophageal motility abnormalities and impaired esophageal bolus transit were more common in patients that underwent gastric banding compared to those that underwent gastric bypass. The majority of symptoms, lesions and abnormalities induced by gastric banding were decreased by conversion to gastric bypass. Esophagitis was present in 28/68 (41 %) and 13/47 (28 %) patients in the band-to-bypass group, pre- versus postoperatively, respectively, (p < 0.05). The percentage of swallows with normal bolus transit increased following transformation from gastric band to gastric bypass (57.9 ± 4.1 and 83.6 ± 3.4 %, respectively, p < 0.01).

conclusionsFrom an esophageal perspective, gastric bypass surgery induces less motility disorders and esophageal symptoms and should be therefore favored over gastric banding in difficult to treat obese patients at risk of repeated bariatric surgery.

Indexed as

Gastric BypassGastroplastyAdultAgedEsophageal MucosaEsophagoscopyFemaleFollow-Up StudiesGastroesophageal RefluxHumansMaleManometryMiddle AgedObesity, MorbidProspective StudiesTreatment OutcomeBariatric surgeryEndoscopyImpedance–manometryObesity

Identifiers

PMID27287911
OpenAlexW2410373751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.