Deconvolution of the cellular origin in hepatocellular carcinoma: Hepatocytes take the center stage.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Single-cell transcriptome analysis reveals the metabolic changes and the prognostic value of malignant hepatocyte subpopulations and predict new therapeutic agents for hepatocellular carcinoma.Frontiers in oncology · 2023
   Article
2. Addressing the liver progenitor cell response and hepatic oxidative stress in experimental non-alcoholic fatty liver disease/non-alcoholic steatohepatitis using amniotic epithelial cells.Stem cell research & therapy · 2021
   Article
3. Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function.Hepatology (Baltimore, Md.) · 2021
   Article
4. A Bioinformatics Analysis Identifies the Telomerase Inhibitor MST-312 for Treating High-STMN1-Expressing Hepatocellular Carcinoma.Journal of personalized medicine · 2021
   Article
5. The cellular origins of cancer with particular reference to the gastrointestinal tract.International journal of experimental pathology · 2020
   Review
6. Stem Cell Therapy for Hepatocellular Carcinoma: Future Perspectives.Advances in experimental medicine and biology · 2020
   Review
7. Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas.Oncotarget · 2017
   Article
8. Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis.Gastroenterology · 2017
   Review

Corrections and comments

• Comment on
  Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice.2016

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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