ArticleGenome biology2016
The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals insights into the basis of parasitism and virulence.
Article in Genome biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 186 citations in OpenAlex.
- Population structure and punctuated genomic hyper-diversity in Caenorhabditis briggsae.Molecular biology and evolution · 2026Article
- The stage-specific regulation and role of root-knot nematode SWEET genes.PLoS pathogens · 2026Article
- Nanoclay-based dsRNA delivery: a novel approach to control Globodera rostochiensis.Molecular biology reports · 2026Article
- Identification of a stylet-secreted effector protein family as a core component of root-knot nematode feeding tubes.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Profiling DNA-protein interactions in Meloidogyne incognita using dCas9-based affinity purification.Plant methods · 2026Article
- Ultrastructural Description of Amphid Neurons in the Pine Wood Nematode Indicates Concurrent Evolution of the Stylet and Specific Neurons.The Journal of comparative neurology · 2025Article
- The SUbventral-Gland Regulator (SUGR-1) of nematode virulence.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Insights from draft genomes of Heterodera species isolated from field soil samples.BMC genomics · 2025Article
- Genomic and Transcriptomic Analysis of the Polyploidy Cyst Nematode,International journal of molecular sciences · 2025Article
- Article
- The origin, deployment, and evolution of a plant-parasitic nematode effectorome.PLoS pathogens · 2024Article
- Chromosome-level genome assembly of the cereal cyst nematode Heterodera flipjevi.Scientific data · 2024Article
- A gene with a thousand alleles: The hyper-variable effectors of plant-parasitic nematodes.Cell genomics · 2024Article
- Temperature Effects on Expression Levels ofInternational journal of molecular sciences · 2024Article
- A Critical Appraisal of DNA Transfer from Plants to Parasitic Cyst Nematodes.Molecular biology and evolution · 2024Article
- Syncytium Induced by Plant-Parasitic Nematodes.Results and problems in cell differentiation · 2024Review
- The Plant Parasitic Nematodes Database: A Comprehensive Genomic Data Platform for Plant Parasitic Nematode Research.International journal of molecular sciences · 2023Article
- Phylogenomic Analysis of 155 Helminth Species Reveals Widespread Absence of Oxygen Metabolic Capacity.Genome biology and evolution · 2023Article
- Comparative genomics among cyst nematodes reveals distinct evolutionary histories among effector families and an irregular distribution of effector-associated promoter motifs.Molecular ecology · 2023Article
- An eggshell-localised annexin plays a key role in the coordination of the life cycle of a plant-parasitic nematode with its host.PLoS pathogens · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
34 authors at 14 institutions in 6 countries.
Funding
Abstract
backgroundThe yellow potato cyst nematode, Globodera rostochiensis, is a devastating plant pathogen of global economic importance. This biotrophic parasite secretes effectors from pharyngeal glands, some of which were acquired by horizontal gene transfer, to manipulate host processes and promote parasitism. G. rostochiensis is classified into pathotypes with different plant resistance-breaking phenotypes.
resultsWe generate a high quality genome assembly for G. rostochiensis pathotype Ro1, identify putative effectors and horizontal gene transfer events, map gene expression through the life cycle focusing on key parasitic transitions and sequence the genomes of eight populations including four additional pathotypes to identify variation. Horizontal gene transfer contributes 3.5 % of the predicted genes, of which approximately 8.5 % are deployed as effectors. Over one-third of all effector genes are clustered in 21 putative 'effector islands' in the genome. We identify a dorsal gland promoter element motif (termed DOG Box) present upstream in representatives from 26 out of 28 dorsal gland effector families, and predict a putative effector superset associated with this motif. We validate gland cell expression in two novel genes by in situ hybridisation and catalogue dorsal gland promoter element-containing effectors from available cyst nematode genomes. Comparison of effector diversity between pathotypes highlights correlation with plant resistance-breaking.
conclusionsThese G. rostochiensis genome resources will facilitate major advances in understanding nematode plant-parasitism. Dorsal gland promoter element-containing effectors are at the front line of the evolutionary arms race between plant and parasite and the ability to predict gland cell expression a priori promises rapid advances in understanding their roles and mechanisms of action.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.