ArticleVision research2017
Assessing the spatial relationship between fixation and foveal specializations.
Article in Vision research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Sub-cone visual acuity can be achieved with less than 1 arcmin retinal slip.Journal of vision · 2026Article
- Assessing the Relationship between Foveal Cone Density, Outer Nuclear Layer Thickness and Foveal Morphology.Ophthalmology science · 2026Article
- Roadmap on advances in visual and physiological optics.Journal of optics (2010) · 2025Review
- In-Vivo Characterization of Healthy Retinal Pigment Epithelium and Photoreceptor Cells from AO-(T)FI Imaging.Vision (Basel, Switzerland) · 2025Article
- Asymmetries in Foveal Vision.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Advanced Analysis Tools for Two Wavelength Autofluorescence Imaging of Macular Xanthophyll Carotenoids: ALSTAR2 Baseline.Translational vision science & technology · 2025Observational
- In Vivo Cone Photoreceptor Topography of the Human Foveola.Investigative ophthalmology & visual science · 2025Article
- High Resolution Imaging and Fixation Analysis of Eccentric Preferred Retinal Loci in Macular Diseases.Investigative ophthalmology & visual science · 2025Article
- The fundamentals of eye tracking part 3: How to choose an eye tracker.Behavior research methods · 2025Article
- Article
- Asymmetries in foveal vision.bioRxiv : the preprint server for biology · 2024Article
- Article
- The preferred retinal loci when the eyes converge.Journal of vision · 2024Article
- High refresh rate display for natural monocular viewing in AOSLO psychophysics experiments.Optics express · 2024Article
- Age-Related Macular Degeneration, a Mathematically Tractable Disease.Investigative ophthalmology & visual science · 2024Review
- Alignment, calibration, and validation of an adaptive optics scanning laser ophthalmoscope for high-resolution human foveal imaging.Applied optics · 2024Article
- The effect of sampling window size on topographical maps of foveal cone density.Frontiers in ophthalmology · 2024Article
- Foveal Cone Structure in Patients With Blue Cone Monochromacy.Investigative ophthalmology & visual science · 2022Article
- Intergrader agreement of foveal cone topography measured using adaptive optics scanning light ophthalmoscopy.Biomedical optics express · 2022Article
- Impact of Reference Center Choice on Adaptive Optics Imaging Cone Mosaic Analysis.Investigative ophthalmology & visual science · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Increased cone photoreceptor density, an avascular zone (FAZ), and the displacement of inner retinal neurons to form a pit are distinct features of the human fovea. As the fovea provides the majority of our vision, appreciating how these anatomical specializations are related is important for understanding foveal development, normal visual function, and retinal disease. Here we evaluated the relationship between these specializations and their location relative to the preferred retinal locus of fixation (PRL). We measured foveal pit volume, FAZ area, peak cone density, and location of the PRL in 22 subjects with normal vision using optical coherence tomography and adaptive optics scanning light ophthalmoscopy. Foveal pit volume was positively correlated with FAZ area; however, peak cone density was not correlated with pit volume. In addition, there was no systematic offset of the location of any of these specializations relative to PRL, and there was no correlation between the magnitude of the offset from PRL and the corresponding foveal specialization measurements (pit volume, FAZ area, peak cone density). The standard deviation of our PRL measurements was consistent with previous measurements of fixational stability. These data provide insight into the sequence of events during foveal development and may have implications for visual function and retinal disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.