ArticleEnvironmental health perspectives2017
Placental Pathology Associated with Household Air Pollution in a Cohort of Pregnant Women from Dar es Salaam, Tanzania.
Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ambient and household PM2.5 pollution and adverse perinatal outcomes: A meta-regression and analysis of attributable global burden for 204 countries and territories.PLoS medicine · 2021Pooled it
- Household air pollution exposures over pregnancy and maternal blood pressure trajectories through 8 years postpartum: Evidence from the Ghana Randomized Air Pollution and Health Study (GRAPHS).Environmental research · 2026Trial
- Effects of a liquefied petroleum gas stove intervention on stillbirth, congenital anomalies and neonatal mortality: A multi-country household air pollution intervention network trial.Environmental pollution (Barking, Essex : 1987) · 2024Trial
- Prenatal Household Air Pollution Exposure and Childhood Blood Pressure in Rural Ghana.Environmental health perspectives · 2024Trial
- A secondary data analysis of a cluster randomized controlled trial: improved cookstoves associated with reduction in incidence of low birthweight in rural Malawi.International journal of epidemiology · 2022Trial
- Who Actually Dies from Indoor Air Pollution? A Forensic Perspective.Diagnostics (Basel, Switzerland) · 2026Review
- Exploring Effects of Household Air Pollution on Pregnant Mothers and Their Offspring in Africa: A Scoping Review.International journal of environmental research and public health · 2026Article
- Maternal PMReproductive toxicology (Elmsford, N.Y.) · 2026Article
- Personal PM2.5 exposure and lung function among adults with and without HIV who have recovered from pneumonia in Kampala, Uganda.Annals of the American Thoracic Society · 2026Article
- The spatial and contextual exposome and subtypes of hypertensive disorders of pregnancy: a double machine learning-based analysis.Exposome · 2026Article
- Article
- Author correction: Association between exposure to particulate matter during pregnancy and birthweight: A systematic review and a meta-analysis of birth cohort studies.Journal of biomedical research · 2025Article
- The effect of air pollution exposure on foetal growth restriction in pregnant women who conceived by in vitro fertilisation a cross-sectional study.Scientific reports · 2025Article
- Household Air Pollution Related to Housing Characteristics and Cooking Conditions in Jimma Town, Ethiopia.Ethiopian journal of health sciences · 2024Article
- Investigating the temporal dynamics of sub-micron particles and particle-bound transition metals in indoor air of a metropolitan city.Environmental geochemistry and health · 2024Article
- Exposure to household air pollution and childhood multimorbidity risk in Jimma, Ethiopia.Frontiers in public health · 2024Article
- Duration-sensitive association between air pollution exposure and changes in cardiometabolic biomarkers: Evidence from a predominantly African American cohort.Environmental research · 2024Article
- DNA methylation profiles reveal sex-specific associations between gestational exposure to ambient air pollution and placenta cell-type composition in the PRISM cohort study.Clinical epigenetics · 2023Article
- Exposure-response relationships for personal exposure to fine particulate matter (PMThe Lancet. Planetary health · 2023Observational
- Prenatal exposure to air pollution is associated with structural changes in the neonatal brain.Environment international · 2023Article
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9 authors.
Funding
Abstract
backgroundSmoke from the burning of biomass fuels has been linked with adverse pregnancy outcomes such as low birth weight, stillbirth, and prematurity.
objectiveTo identify potential underlying mechanisms of adverse perinatal outcomes, we explored the association of placental pathology with household air pollution in pregnant women from urban/periurban Tanzania who cook predominantly with charcoal.
methodsBetween 2011 and 2013, we measured personal exposures to fine particulate matter (PM2.5) and carbon monoxide (CO) over 72 hr among a cohort of Tanzanian pregnant women. Placentas were collected after delivery for examination. Placental pathologies of inflammatory, hypoxic, ischemic/hypertensive, infectious and thrombotic etiologies were diagnosed, blinded to exposure levels. Using multiple logistic regression, we explored the association of PM2.5 and CO exposure with placental pathology.
resultsOne hundred sixteen women had personal air exposure measurements and placental histopathology available for analysis. PM2.5 and CO exposures were moderate [geometric means (GSD) were 40.5 μg/m3 (17.3) and 2.21 ppm (1.47) respectively]; 88.6% of PM2.5 measurements exceeded World Health Organization air quality guidelines. We observed an increase in the odds (per 1-unit increase in exposure on the ln-scale) of fetal thrombotic vasculopathy (FTV) both with increasing PM2.5 [adjusted odds ratio (aOR) = 5.5; 95% CI: 1.1, 26.8] and CO measurements (aOR = 2.5; 95% CI: 1.0, 6.4) in adjusted models only. FTV also was more common among pregnancies complicated by stillbirth or low birth weight.
conclusionsFetal thrombosis may contribute to the adverse outcomes associated with household air pollution from cook stoves during pregnancy. Larger studies are necessary for confirmation. Citation: Wylie BJ, Matechi E, Kishashu Y, Fawzi W, Premji Z, Coull BA, Hauser R, Ezzati M, Roberts D. 2017. Placental pathology associated with household air pollution in a cohort of pregnant women from Dar es Salaam, Tanzania. Environ Health Perspect 125:134-140; http://dx.doi.org/10.1289/EHP256.
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