ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Are patients with lichen planus really prone to urolithiasis? Lichen planus and urolithiasis.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 6 citations in OpenAlex.
- Study on the potential links between clinical features of oral lichenoid mucositis and systemic diseases.BMC oral health · 2025Article
- Prevalence and risk of chronic kidney disease in oral lichen planus: a large cross-sectional study from eastern China.Annals of translational medicine · 2021Article
- Bullous Lichen Planus: Case Report and Review.Journal of pharmacy & bioallied sciences · 2019Article
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6 authors at 6 institutions in 2 countries.
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Abstract
purposeto investigate whether patients with lichen planus (LP) are really prone to urolithiasis or not. PATIENTS AND
methodsWe performed a prospective analysis of 40 patients diagnosed with lichen planus (LP) (group I), and 40 volunteers did not have LP before (group II). Participants were all checked for urolithiasis by radiological investigations. Blood samples were analyzed for biochemistry parameters including calcium and uric acid. 24-h urine samples were analyzed to investigate oxalate, citrate calcium, uric acid, magnesium, sodium and creatinine.
resultsMen/women ratio and mean age were similar between group I and II (p>0.05). A presence or history of urolithiasis was detected in 8 (20%) and 2 (%5) patients in group I and II, respectively (p<0.05). Hypocitraturia was the most common anomaly with 35% (n:14) in group I. The rate of hypocitraturia in group II was 12.5% (n:5) and the difference was statistically significantly different (p=0.036). In group I, hyperuricosuria and hyperoxaluria followed with rates of 27.5% (n:11) and 25% (n:10), respectively. The rate of hyperuricosuria and hyperoxaluria were both 5% (n:2) in group II and the differences were significant (p<0.05). Hyperuricemia was another importante finding in the patients with LP. It was detected in 13 (32.5%) patients in group I and in 1 (2.5%) participant in group II (p=0.001).
conclusionAccording to our results, metabolic disorders of urolithiasis were highly detected in the patients with LP. However, similar to the etiology of LP, the exact reasons for these metabolic abnormalities in LP remain a mystery.
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