ArticleJournal of affective disorders2016
Antenatal depression and adversity in urban South Africa.
Article in Journal of affective disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 7 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
69 citing papers in PubMed, 7 syntheses or guidelines pooled it, 161 citations in OpenAlex.
- Screening tools for maternal mental health in Africa: a systematic review.Frontiers in global women's health · 2026Pooled it
- The epidemiology of maternal mental health in Africa: a systematic review.Archives of women's mental health · 2025Pooled it
- The relationship between social support and mental health problems during pregnancy: a systematic review and meta-analysis.Reproductive health · 2021Pooled it
- Prevalence and determinants of antenatal common mental disorders among women in India: a systematic review and meta-analysis.Archives of women's mental health · 2021Pooled it
- The epidemiology of postnatal depression in Ethiopia: a systematic review and meta-analysis.Reproductive health · 2020Pooled it
- Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2020Pooled it
- Pooled it
- Task-sharing of psychological treatment for antenatal depression in Khayelitsha, South Africa: Effects on antenatal and postnatal outcomes in an individual randomised controlled trial.Behaviour research and therapy · 2020Trial
- Perinatal depressive symptoms among low-income South African women at risk of depression: trajectories and predictors.BMC pregnancy and childbirth · 2019Trial
- The sertraline metabolite, desmethylsertraline, may be implicated in adverse outcomes reported after gestational sertraline use: insights from a study in zebrafish.Pharmacological reports : PR · 2025Article
- Brief problem-solving therapy (PST) for women experiencing antenatal depressive symptoms: a randomised, controlled feasibility trial in (an) antenatal care setting in rural Ethiopia.Pilot and feasibility studies · 2025Article
- Utilising clinical associates to address mental health service provision challenges in South Africa: the views of healthcare managers and providers.BMC health services research · 2025Article
- Identification of mothers with mental health problems is accidental: perceptions of health care providers on availability, access, and support for maternal mental health care for adolescent mothers in Malawi.BMC health services research · 2024Article
- Antenatal depression among pregnant mothers in Afghanistan: A cross-sectional study.BMC pregnancy and childbirth · 2024Article
- Food insecurity and perinatal depression among pregnant women in BUNMAP cohort in Ethiopia: a structural equation modelling.Public health nutrition · 2024Article
- Perinatal anxiety disorders screening study: a study protocol.BMC psychiatry · 2024Article
- Mental illness attitudes, service provision interest and further training preferences of clinical associates.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024Article
- Understanding of perinatal mental health and its psychosocial determinants through Ukrainian women's experience.European journal of midwifery · 2024Article
- Common Mental Disorder and Associated Factors among Women Attending Antenatal Care Follow-Up in North Wollo Public Health Facilities, Amhara Region, Northeast Ethiopia: A Cross-Sectional Study.Depression research and treatment · 2024Article
- Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundIn low and middle-income countries (LMIC), common mental disorders affecting pregnant women receive low priority, despite their disabling effect on maternal functioning and negative impact on child health and development. We investigated the prevalence of risk factors for antenatal depression among women living in adversity in a low-resource, urban setting in Cape Town, South Africa.
methodsThe MINI Neuropsychiatric Interview (MINI Plus) was used to measure the diagnostic prevalence of depression amongst women attending their first antenatal visit at a primary-level, community-based clinic. Demographic data were collected followed by administration of questionnaires to measure psychosocial risk. Analysis examined the association between diagnosis of depression and psychosocial risk variables, and logistic regression was used to investigate predictors for major depressive episode (MDE).
resultsAmong 376 women participating, the mean age was 26 years. The MINI-defined prevalence of MDE was 22%, with 50% of depressed women also expressing suicidality. MDE diagnosis was significantly associated with multiple socioeconomic and psychosocial risk factors, including a history of depression or anxiety, food insecurity, experience of threatening life events and perceived support from family. LIMITATIONS: The use of self-report measures may have led to recall bias. Retrospective collection of clinical data limited our ability to examine some known risk factors for mental distress.
conclusionThese findings confirm the high prevalence of MDE among pregnant women in LMIC settings. Rates of depression may be increased in settings where women are exposed to multiple risks. These risk factors should be considered when planning maternal mental health interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.