Evidence map›Paper›PMID 27284453›Full record

ArticleEndocrinology, diabetes & metabolism case reports2016

Successful treatment of a prolactinoma with the antipsychotic drug aripiprazole.

Ilse C A Bakker, Chris D Schubart, Pierre M J Zelissen

Open access · goldAbstract read
In one paragraph

Article in Endocrinology, diabetes & metabolism case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Treatment of Prolactinoma.Medicina (Kaunas, Lithuania) · 2022
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ilse C A BakkerDepartment of Internal Medicine, Section of Endocrinology , University Medical Center Utrecht, Utrecht , The Netherlands.
Chris D SchubartDepartment of Psychiatry , Tergooi Hospital, Hilversum , The Netherlands.
Pierre M J ZelissenDepartment of Internal Medicine, Section of Endocrinology , University Medical Center Utrecht, Utrecht , The Netherlands.
University Medical Center Utrecht · NLTergooi · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledIn this report, we describe a female patient with both prolactinoma and psychotic disorder who was successfully treated with aripiprazole, a partial dopamine 2 receptor agonist. During the follow-up of more than 10 years, her psychotic symptoms improved considerably, prolactin levels normalised and the size of the prolactinoma decreased. This observation may be of clinical relevance in similar patients who often are difficult to treat with the regular dopaminergic drugs. LEARNING POINTS: Prolactinoma coinciding with psychosis can represent a therapeutic challenge.In contrast to many other antipsychotic drugs, aripiprazole is associated with a decrease in prolactin levels.Aripiprazole can be a valuable pharmaceutical tool to treat both prolactinoma and psychosis.

Indexed as

2016AdultAmenorrhoeaAntipsychoticsAripiprazoleBromocriptineCabergolineDepressionDopamineDopamine agonistsDopamine receptor agonistsFemaleHallucinationHyperprolactinaemiaInsomniaJuneMicroadenomaMicroprolactinomaMRINetherlandsNovel treatmentPituitaryPituitary adenomaProlactinProlactinomaPsychology/PsychiatryPsychosisQuinagolideWhite

Identifiers

PMID27284453
PMCPMC4898067
OpenAlexW2413166707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.