Evidence map›Paper›PMID 27284450›Full record

ArticleMolecular and clinical oncology2016

Tolerance and efficacy of palliative radiotherapy for advanced pancreatic cancer: A retrospective analysis of single-institutional experiences.

Edyta Wolny-Rokicka, Krzysztof Sutkowski, Aleksandra Grządziel, Żaneta Dorsz, Andrzej Tukiendorf, Jakub Lipiński, Jerzy Wydmański

Abstract read
In one paragraph

Article in Molecular and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  11. Review
  12. Symptom Management in Pancreatic Cancer.Current treatment options in oncology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edyta Wolny-RokickaDepartment of Radiotherapy, Lubuski Center of Oncology, Regional Hospital in Zielona Góra, 65-001 Zielona Góra, Poland; Department of Radiotherapy, Center of Oncology, Maria Sklodowska-Curie Memorial Institute, Gliwice Branch, 44-101 Gliwice, Poland.
Krzysztof SutkowskiFirst Department and Clinic of General, Gastroenterological and Endocrinological Surgery, Wrocław Medical University, 50-369 Wrocław;, Poland.
Aleksandra GrządzielDepartment of Medical Physics, Center of Oncology, Maria Sklodowska-Curie Memorial Institute, Gliwice Branch, 44-101 Gliwice, Poland.
Żaneta DorszDepartment of Radiotherapy, Center of Oncology, Maria Sklodowska-Curie Memorial Institute, Gliwice Branch, 44-101 Gliwice, Poland.
Andrzej TukiendorfDepartment of Epidemiology and Silesia Cancer Registry, Center of Oncology, Maria Sklodowska-Curie Memorial Institute, Gliwice Branch, 44-101 Gliwice, Poland.
Jakub LipińskiUniversity of Zielona Góra, Faculty of Computer, Electrical and Control Engineering, 65-001 Zielona Góra, Poland.
Jerzy WydmańskiDepartment of Radiotherapy, Center of Oncology, Maria Sklodowska-Curie Memorial Institute, Gliwice Branch, 44-101 Gliwice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to investigate hypofractionated radiotherapy (RT) in patients with locally advanced or metastatic adenocarcinoma of the pancreas. A total of 31 patients were enrolled in this study, 26 of whom had locally advanced (M0) pancreatic cancer and 5 had metastatic (M1) disease. The patients were treated with palliative RT (6-30 Gy in 1-10 fractions over a period of 1 day-2 weeks). Treatment-related toxicity was classified according to the Common Terminology Criteria for Adverse Events, version 3.0. Early mild toxicity was observed. A total of 17 patients (55%) achieved good pain control without pharmacological therapy, and 12 patients (39%) reduced their use of analgesics; in the remaining 2 patients (6%), there was no change in analgesic use. Late high-grade (>3) toxicity was not observed. The average survival time for the 31 patients was 9 months. The 1-year overall survival rate was 16%. Palliative RT was well-tolerated and was able to prolong the survival time. The majority of the patients achieved better pain control with palliative RT.

Indexed as

advanced pancreatic cancerhypofractionated radiotherapypainpalliative radiotherapypancreatic cancer

Identifiers

PMID27284450
PMCPMC4887860

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.