ArticleBiomedical reports2016
Association between glycated hemoglobin A1c levels with age and gender in Chinese adults with no prior diagnosis of diabetes mellitus.
Article in Biomedical reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 75 citations in OpenAlex.
- Assessment of Glycemic Control Among Prospective Hajj Pilgrims With Type 2 Diabetes Mellitus in Tangerang City, Indonesia.Journal of the ASEAN Federation of Endocrine Societies · 2026Article
- Reduced varying coefficient models for regional quantile regression with multiple responses.Biometrics · 2026Article
- Glucose 6-phosphate dehydrogenase deficiency and Southeast Asian-specific mutations lower HbADiabetologia · 2025Article
- Determining A1C Normal Values in Rhesus Macaques (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- The Impact of Age and Sex on Fasting Plasma Glucose and Glycated Haemoglobin (HbA1c) in the Non-diabetes Population.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Measuring Hemoglobin A1C with Frozen Packed Cell and Frozen Whole Blood Samples in an Epidemiologic Study: The Reasons for Geographic and Racial Differences in Stroke Study.Journal of clinical laboratory analysis · 2025Article
- Prevalence and Predictors of Albuminuria in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study from the United Arab Emirates.Current diabetes reviews · 2025Article
- Reference interval for glycated hemoglobin (HbA1c) in non-pregnant, non-diabetic women in Ethiopia: a cross-sectional study.The Pan African medical journal · 2025Article
- Age and HbA1c in Diabetes: A Negative Association Modified by Red Cell Characteristics.Journal of clinical medicine · 2024Article
- Clinical biomarker-based biological age predicts deaths in Brazilian adults: the ELSA-Brasil study.GeroScience · 2024Article
- Gender and Age Differences in the Evaluation and Clinical Outcomes of Patients with Palpitations.Journal of general internal medicine · 2024Observational
- The Importance of Fructosamine for Monitoring the Compensation and Effectiveness of Diabetes Treatment.Journal of diabetes science and technology · 2024Article
- Diabetes Mellitus Inequality in South Korean Adults by Region: The Influence of Obesity and Depression.Iranian journal of public health · 2024Article
- Establishment of reference interval for hemoglobin A1C and other hemoglobin subfractions for healthy Saudi adults.PloS one · 2024Article
- Article
- Association between Perceived Protection Motivation, Preventive Behaviors, and Biomarkers among Diabetic Patients in Rural Areas of Thailand.Clinics and practice · 2023Article
- The effect of age and gender on HbA1c levels in adults without diabetes mellitus.Journal of medical biochemistry · 2023Article
- Ethnicity, Age, and Gender Differences in Glycated Hemoglobin (HbA1c) Levels among Adults in Northern and Eastern Sudan: A Community-Based Cross-Sectional Study.Life (Basel, Switzerland) · 2023Article
- Associations of the baseline level and change in glycosylated hemoglobin A1c with incident hypertension in non-diabetic individuals: a 3-year cohort study.Diabetology & metabolic syndrome · 2022Article
- The effect of age and sex on glycated hemoglobin in dogs.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
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5 authors at 1 institution in 1 country.
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Abstract
The present cross-sectional study consisted of 18,265 Chinese patients not previously diagnosed with diabetes mellitus, and who underwent physical examination at the Third People's Hospital of Shenzhen between June 2014 and May 2015 (mean patient age, 51.312±15.252 years). The study was composed of 11,770 males and 6,495 females. The aim was to investigate the association between glycated hemoglobin A1c (HbA1c) levels, gender and age. HbA1c values were measured using a Bio-Rad VARIANT™ II HbA1c Reorder Pack. All data was collected for analysis of the HbA1c levels in different gender and age groups, in order to investigate the association between HbA1c levels and age. Analysis of the 18,265 total cases and 16,734 cases with HbA1c levels <6.5%, demonstrated a positive correlation between levels of HbA1c and patient age. Linear regression for patient age and HbA1c levels demonstrated that HbA1c (%) = 0.020 × age (years) + 4.523 (r=0.369, P<0.0001) and HbA1c (%) = 0.014 × age (years) + 4.659 (r=0.485, P<0.0001), respectively. HbA1c levels of the male group were significantly higher than those of the female group (P<0.0001). Furthermore, in different gender groups, HbA1c levels gradually rose with increasing age. Therefore, HbA1c levels are associated with age and gender in Chinese populations, and this should be considered when selecting HbA1c as a criterion for future diabetes screening.
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