Evidence map›Paper›PMID 27284332›Full record

ArticleExperimental and therapeutic medicine2016

Donepezil delays photoreceptor apoptosis induced by N-methyl-N-nitrosourea in mice.

Longyan Wu, Man Xu, Shengtao Liu, Guo Chen, Fengjun Zhang, Yao Zhao, Jinglin Yi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Urtica dioica extracts abolish scopolamine-induced neuropathies in rats.Environmental science and pollution research international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Longyan WuDepartment of Ophthalmology, Affiliated Eye Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Man XuDepartment of Ophthalmology, Affiliated Eye Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Shengtao LiuDepartment of Ophthalmology, Affiliated Eye Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Guo ChenDepartment of Ophthalmology, Affiliated Eye Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Fengjun ZhangDepartment of Ophthalmology, Affiliated Eye Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Yao ZhaoDepartment of Ophthalmology, Affiliated Eye Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Jinglin YiDepartment of Ophthalmology, Affiliated Eye Hospital, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is a group of inherited retinal degeneration diseases characterized by photoreceptor cell death that causes visual disturbances and eventual blindness. Intraperitoneal injection of N-methyl-N-nitrosourea (MNU) causes photoreceptor loss, and is used to create an animal model for investigating the mechanisms that cause retinal degeneration diseases. Donepezil is an acetylcholinesterase inhibitor that has a protective effect on retinal ganglion cells

Indexed as

B-cell lymphoma-2donepezilheat shock protein 70N-methyl-N-nitrosoureaphotoreceptor apoptosis

Identifiers

PMID27284332
PMCPMC4887835
OpenAlexW2323240666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.