Evidence map›Paper›PMID 27284241›Full record

ArticlePatient preference and adherence2016

Anxiety and depression correlate with disease and quality-of-life parameters in Chinese patients with ankylosing spondylitis.

Xujuan Xu, Biyu Shen, Aixian Zhang, Jingwei Liu, Zhanyun Da, Hong Liu, Zhifeng Gu

Open access · goldAbstract read
In one paragraph

Article in Patient preference and adherence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A Nomogram Predicting Decreased Quality of Life in Patients with Keloids.Clinical, cosmetic and investigational dermatology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Effects of depression on patients suffering from ankylosing spondylitis: a comparative study.Sao Paulo medical journal = Revista paulista de medicina · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Alexithymia in ankylosing spondylitis.Turkish journal of physical medicine and rehabilitation · 2021
    Article
  12. Observational
  13. Observational
  14. Article
  15. Article
  16. Impulsivity and ankylosing spondylitis: Is there a relationship?Turkish journal of physical medicine and rehabilitation · 2019
    Article
  17. Article
  18. [Functional outcomes of patients receiving total hip arthroplasty for ankylosing spondylitis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018
    Article
  19. Article
  20. Intervention of the Nuss Procedure on the Mental Health of Pectus Excavatum Patients.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xujuan XuDepartment of Nursing, Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Biyu ShenSchool of Nursing, Nantong University, Nantong, People's Republic of China; Department of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Aixian ZhangDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Jingwei LiuDepartment of Nursing, The Second Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Zhanyun DaDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Hong LiuDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Zhifeng GuDepartment of Rheumatology, Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Affiliated Hospital of Nantong University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the relationship between mental and physical health in Chinese patients with ankylosing spondylitis (AS) and to identify the predictors of psychological status.

methodsPatients with AS (n=103) and healthy controls (n=121) were surveyed between 2010 and 2011 (cross-sectional study). The Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Metrology Index, pain visual analog scale, Health Assessment Questionnaire, revised Self-Rating Anxiety Scale, revised Self-Rating Depression Scale, and Short-Form 36 questionnaire were administered.

resultsThe frequency of anxiety and depression in patients with AS was higher than that in healthy controls (P<0.001). Severe disease status and reduced quality of life (QoL) were associated with anxiety and depression. Disease activity and somatic pain were more severe in the anxious and depressed subgroups. Impaired physical functioning (assessed by Bath Ankylosing Spondylitis Functional Index) was higher in the anxious and depressed subgroups, while measures of spinal mobility (assessed by Bath Ankylosing Spondylitis Metrology Index) were not associated with depression. Lower QoL was observed in the depressed subgroup.

conclusionLow socioeconomic status, lack of health insurance, and fatigue contributed to depression in Chinese patients with AS. These patients may require a psychological care approach that is different from those of other countries.

Indexed as

ankylosing spondylitisdisease activitypsychological statusquality of life

Identifiers

PMID27284241
PMCPMC4881928
OpenAlexW2400558536

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.