Evidence map›Paper›PMID 27284058›Full record

ReviewBiochemical Society transactions2016

Transport mechanism of a glutamate transporter homologue GltPh.

Yurui Ji, Vincent L G Postis, Yingying Wang, Mark Bartlam, Adrian Goldman

Open access · hybridAbstract readReview
In one paragraph

Review in Biochemical Society transactions, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Advanced optical microscopy methods forBiophysical reviews · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Yurui JiCollege of Environmental Science and Engineering, Nankai University, Tianjin 300071, China Astbury Centre for Structural Molecular Biology, School of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, U.K.
Vincent L G PostisAstbury Centre for Structural Molecular Biology, School of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, U.K. Biomedicine Research Group, Faculty of Health and Social Sciences, Leeds Beckett University, Leeds, LS1 3JT, U.K.
Yingying WangCollege of Environmental Science and Engineering, Nankai University, Tianjin 300071, China.
Mark BartlamAstbury Centre for Structural Molecular Biology, School of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, U.K. College of Life Sciences, Nankai University, Tianjin 300071, China bartlam@nankai.edu.cn a.goldman@leeds.ac.uk.
Adrian GoldmanAstbury Centre for Structural Molecular Biology, School of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, U.K. College of Life Sciences, Nankai University, Tianjin 300071, China Division of Biochemistry, Department of Biosciences, University of Helsinki, Helsinki, FIN-00014, Finland bartlam@nankai.edu.cn a.goldman@leeds.ac.uk.
Nankai University · CN

Funding

Biotechnology and Biological Sciences Research Council BB/M021610/1Wellcome Trust 019322/7/10/Z
6 · The paper itself

Abstract

Glutamate transporters are responsible for uptake of the neurotransmitter glutamate in mammalian central nervous systems. Their archaeal homologue GltPh, an aspartate transporter isolated from Pyrococcus horikoshii, has been the focus of extensive studies through crystallography, MD simulations and single-molecule FRET (smFRET). Here, we summarize the recent research progress on GltPh, in the hope of gaining some insights into the transport mechanism of this aspartate transporter.

Indexed as

Amino Acid Transport System X-AGAspartic AcidBiological TransportProtein ConformationPyrococcus horikoshiiSubstrate SpecificityAmino Acid Transport System X-AGAspartic Acidaspartate transporterCl− conductanceexcitatory amino acid transporters (EAATs)GltPhglutamate transporterNa+ coupling

Identifiers

PMID27284058
PMCPMC4900748
OpenAlexW2396501900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.