Evidence map›Paper›PMID 27284057›Full record

ReviewBiochemical Society transactions2016

Lysosomal and vacuolar sorting: not so different after all!

Carine de Marcos Lousa, Jurgen Denecke

Open access · hybridAbstract readReview
In one paragraph

Review in Biochemical Society transactions, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. The Toxoplasma plant-like vacuolar compartment (PLVAC).The Journal of eukaryotic microbiology · 2022
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Carine de Marcos LousaSchool of Clinical and Applied Sciences, Faculty of Biomedical Sciences, Leeds Beckett University, Leeds LS13HE, U.K. Centre for Plant Sciences, University of Leeds, Leeds LS29JT, U.K. c.de-marcos-lousa@leedsbeckett.ac.uk j.denecke@leeds.ac.uk.
Jurgen DeneckeCentre for Plant Sciences, University of Leeds, Leeds LS29JT, U.K. c.de-marcos-lousa@leedsbeckett.ac.uk j.denecke@leeds.ac.uk.
University of Leeds · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D016223/1Biotechnology and Biological Sciences Research Council BB/K007181/1
6 · The paper itself

Abstract

Soluble hydrolases represent the main proteins of lysosomes and vacuoles and are essential to sustain the lytic properties of these organelles typical for the eukaryotic organisms. The sorting of these proteins from ER residents and secreted proteins is controlled by highly specific receptors to avoid mislocalization and subsequent cellular damage. After binding their soluble cargo in the early stage of the secretory pathway, receptors rely on their own sorting signals to reach their target organelles for ligand delivery, and to recycle back for a new round of cargo recognition. Although signals in cargo and receptor molecules have been studied in human, yeast and plant model systems, common denominators and specific examples of diversification have not been systematically explored. This review aims to fill this niche by comparing the structure and the function of lysosomal/vacuolar sorting receptors (VSRs) from these three organisms.

Indexed as

AnimalsFungal ProteinsHumansLysosomal Membrane ProteinsLysosomesMembrane Transport ProteinsPlant ProteinsPlantsProtein ConformationProtein TransportSaccharomyces cerevisiaeVacuolesVesicular Transport ProteinsFungal ProteinsLysosomal Membrane ProteinsMembrane Transport ProteinsPlant ProteinsVesicular Transport Proteinsendosomal sortinglysosomesreceptorstraffickingvacuole

Identifiers

PMID27284057
PMCPMC5264500
OpenAlexW2416458206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.