Evidence map›Paper›PMID 27283998›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2017

In vivo visualization using MRI T

Ferenc Tóth, Frédéric H David, Elizabeth LaFond, Luning Wang, Jutta M Ellermann, Cathy S Carlson

Open access · greenAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Longitudinal In Vivo 3T MRI of Naturally Occurring Early Osteochondrosis Lesions in the Piglet Humeral Epiphyseal Cartilage and Growth Plate.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  3. Review
  4. Article
  5. Naturally occurring osteochondrosis latens lesions identified by quantitative and morphological 10.5 T MRI in pigs.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023
    Article
  6. Article
  7. Evaluation of the Suitability of Miniature Pigs as an Animal Model of Juvenile Osteochondritis Dissecans.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ferenc TóthDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 435 AnSci/VetMed, 1988 Fitch Avenue, St. Paul, Minnesota, 55108.
Frédéric H DavidDepartment of Veterinary Clinical Sciences, University of Minnesota, St. Paul, Minnesota.
Elizabeth LaFondDepartment of Veterinary Clinical Sciences, University of Minnesota, St. Paul, Minnesota.
Luning WangCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota.
Jutta M EllermannCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota.
Cathy S CarlsonDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 435 AnSci/VetMed, 1988 Fitch Avenue, St. Paul, Minnesota, 55108.
University of Minnesota · USResonance Research (United States) · US

Funding

Comparative Medicine and Pathology TrainingT32OD010993 · OD · UNIVERSITY OF MINNESOTA · PI DAVID R BROWN, Cathy S. Carlson · 2012 to 2026
$6.2M
Development and MRI characterization of a goat model of human osteochondrosisK01OD021293 · OD · UNIVERSITY OF MINNESOTA · PI TOTH, FERENC · 2015 to 2019
$650k
In Vivo MRI Characterization of an Animal Model of OsteochondrosisR21AR065385 · NIAMS · UNIVERSITY OF MINNESOTA · PI CARLSON, CATHY S. · 2014 to 2015
$354k
Diagnosis of Osteochondrosis using high field MRIK18OD010468 · OD · UNIVERSITY OF MINNESOTA · PI CARLSON, CATHY S. · 2012 to 2013
$290k
NIAMS NIH HHS R21 AR065385NIH HHS K01 OD021293NIH HHS K18 OD010468NIH HHS T32 OD010993
6 · The paper itself

Abstract

In vivo visualization of subclinical osteochondrosis (OC) lesions, characterized by necrosis of epiphyseal growth cartilage, is necessary to clarify the pathogenesis of this disease. Hence, our objectives were to demonstrate induced necrosis of the epiphyseal cartilage in vivo using MRI and to monitor progression or resolution of resulting lesions. We also aimed to improve the goat model of OC by introducing controlled exercise. Vascular supply to the epiphyseal cartilage was surgically interrupted in four 5-day-old goats to induce ischemic cartilage necrosis in a medial femoral condyle. Starting 3 weeks postoperatively, goats underwent daily controlled exercise until euthanasia at 6, 10, 11 (n = 2) weeks postoperatively. T

Indexed as

Physical Conditioning, AnimalAnimalsCartilage, ArticularDisease Models, AnimalFemurGoatsGrowth PlateImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNecrosisOsteochondritis DissecansOsteochondrosiscartilage necrosisMRIosteochondritis dissecansosteochondrosisT2 map

Identifiers

PMID27283998
PMCPMC5458739
OpenAlexW2412344247

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.