Evidence map›Paper›PMID 27283459›Full record

ArticleScientific reports2016

Color calibration and fusion of lens-free and mobile-phone microscopy images for high-resolution and accurate color reproduction.

Yibo Zhang, Yichen Wu, Yun Zhang, Aydogan Ozcan

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Evaluation of native canine skin color by smartphone-based dermatoscopy.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2022
    Article
  4. Deep learning in optical metrology: a review.Light, science & applications · 2022
    Review
  5. Thermotropic Liquid Crystals for Temperature Mapping.Frontiers in bioengineering and biotechnology · 2022
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yibo ZhangElectrical Engineering Department, University of California, Los Angeles, CA, 90095, USA.
Yichen WuElectrical Engineering Department, University of California, Los Angeles, CA, 90095, USA.
Yun ZhangElectrical Engineering Department, University of California, Los Angeles, CA, 90095, USA.
Aydogan OzcanElectrical Engineering Department, University of California, Los Angeles, CA, 90095, USA.

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Lens-free holographic microscopy can achieve wide-field imaging in a cost-effective and field-portable setup, making it a promising technique for point-of-care and telepathology applications. However, due to relatively narrow-band sources used in holographic microscopy, conventional colorization methods that use images reconstructed at discrete wavelengths, corresponding to e.g., red (R), green (G) and blue (B) channels, are subject to color artifacts. Furthermore, these existing RGB colorization methods do not match the chromatic perception of human vision. Here we present a high-color-fidelity and high-resolution imaging method, termed "digital color fusion microscopy" (DCFM), which fuses a holographic image acquired at a single wavelength with a color-calibrated image taken by a low-magnification lens-based microscope using a wavelet transform-based colorization method. We demonstrate accurate color reproduction of DCFM by imaging stained tissue sections. In particular we show that a lens-free holographic microscope in combination with a cost-effective mobile-phone-based microscope can generate color images of specimens, performing very close to a high numerical-aperture (NA) benchtop microscope that is corrected for color distortions and chromatic aberrations, also matching the chromatic response of human vision. This method can be useful for wide-field imaging needs in telepathology applications and in resource-limited settings, where whole-slide scanning microscopy systems are not available.

Indexed as

Cell PhoneColorAlgorithmsCalibrationHolographyLensesMicroscopy

Identifiers

PMID27283459
PMCPMC4901265

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.