Evidence map›Paper›PMID 27283385›Full record

ArticleAdvanced healthcare materials2016

Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria.

Xuan Chen, Bin Wu, Kalana W Jayawardana, Nanjing Hao, H Surangi N Jayawardena, Robert Langer, Ana Jaklenec, Mingdi Yan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuan ChenDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.
Bin WuDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.
Kalana W JayawardanaDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.
Nanjing HaoDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.
H Surangi N JayawardenaDavid H. Koch Institute of Integrative Cancer Research Centre, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Robert LangerDavid H. Koch Institute of Integrative Cancer Research Centre, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Ana JaklenecDavid H. Koch Institute of Integrative Cancer Research Centre, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Mingdi YanDepartment of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.

Funding

Photogenerated Carbohydrate MicroarraysR01GM080295 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2008 to 2012
$2.0M
Maltoheptaose based nanotherapeutics for multidrug resistant bacterial infectionR21AI109896 · NIAID · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2014 to 2015
$444k
NIAID NIH HHS R21 AI109896NIGMS NIH HHS R01 GM080295
6 · The paper itself

Abstract

A multivalent trehalose-grafted poly(lactic acid) is synthesized and encapsulated with iron oxide magnetic nanoparticles. The magnetic micelles interact with Mycobacterium smegmatis to form orange clusters. Very little particle interaction is found on Staphylococcus epidermidis 35984 or Escherichia coli ORN 208. The presented new approach to the detection of mycobacteria does not require molecular biology reagents or sophisticated instruments.

Indexed as

Bacterial Typing TechniquesEscherichia coliMagnetite NanoparticlesMycobacterium smegmatisStaphylococcus epidermidisTrehaloseMagnetite NanoparticlesTrehaloseglycopolymermagnetic micellesmycobacteriumpoly(lactic acid)trehalose

Identifiers

PMID27283385
PMCPMC5242184

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.