Evidence map›Paper›PMID 27283030›Full record

ArticleCancer research and treatment2017

Human Herpesvirus 8-Unrelated Primary Effusion Lymphoma-Like Lymphoma in an Elderly Korean Patient with a Good Response to Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone.

Junghoon Shin, Jeong-Ok Lee, Ji-Young Choe, Soo-Mee Bang, Jong-Seok Lee

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Junghoon ShinDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Jeong-Ok LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Ji-Young ChoeDepartment of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea.
Soo-Mee BangDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Jong-Seok LeeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Seoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary effusion lymphoma (PEL) is a rare type of non-Hodgkin's lymphoma arising from a B-cell lineage characterized by the formation of malignant effusion in body cavities without evidence of a detectable tumor. The effusion contains tumor cells universally infected with human herpesvirus 8 (HHV8), which is the critical factor differentiating PEL from HHV8-unrelated PEL-like lymphoma (PEL-LL). This report describes a 77-year-old male patient with pleural effusion and ascites, containing lymphoma cells expressing a B-cell phenotype, but without markers of HHV8 in immunocytochemical analysis. The patient was diagnosed with PEL-LL and treated with six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP), which resulted in a complete remission. The patient is currently disease-free 15 months post-treatment. To the best of our knowledge, this is the first report on administration of R-CHOP in a PEL-LL patient in South Korea.

Indexed as

Herpesvirus 8, HumanAgedAge FactorsAntibodies, Monoclonal, Murine-DerivedAntineoplastic Combined Chemotherapy ProtocolsBiomarkersBiopsyCyclophosphamideDoxorubicinHerpesviridae InfectionsHumansLymphoma, Primary EffusionMaleMultimodal ImagingPrednisoneRemission InductionAntibodies, Monoclonal, Murine-DerivedBiomarkersCyclophosphamideDoxorubicinPrednisoneR-CHOP protocolRituximabVincristineHuman herpesvirus 8Primary effusion lymphomaR-CHOP protocol

Identifiers

PMID27283030
PMCPMC5266403
OpenAlexW2417659135

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.