Evidence map›Paper›PMID 27283002›Full record

SynthesisBMC psychiatry2016

Neural correlates of conversion disorder: overview and meta-analysis of neuroimaging studies on motor conversion disorder.

Markus Boeckle, Gregor Liegl, Robert Jank, Christoph Pieh

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in BMC psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Impaired Action Control in Patients With Functional Movement Disorders.The Journal of neuropsychiatry and clinical neurosciences · 2020
    Article
  18. Article
  19. Hallucinations, somatic-functional disorders of PD-DLB as expressions of thalamic dysfunction.Movement disorders : official journal of the Movement Disorder Society · 2019
    Review
  20. Sexual abuse and psychogenic nonepileptic seizures.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Markus BoeckleDepartment of Psychotherapy and Biopsychosocial Health, Danube University Krems, Dr.-Karl-Dorrek-Str. 30, 3500, Krems, Austria. markus.boeckle@donau-uni.ac.at.
Gregor LieglDepartment of Psychotherapy and Biopsychosocial Health, Danube University Krems, Dr.-Karl-Dorrek-Str. 30, 3500, Krems, Austria.
Robert JankDepartment of Psychotherapy and Biopsychosocial Health, Danube University Krems, Dr.-Karl-Dorrek-Str. 30, 3500, Krems, Austria.
Christoph PiehDepartment of Psychotherapy and Biopsychosocial Health, Danube University Krems, Dr.-Karl-Dorrek-Str. 30, 3500, Krems, Austria.
Universität für Weiterbildung Krems · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConversion Disorders (CD) are prevalent functional disorders. Although the pathogenesis is still not completely understood, an interaction of genetic, neurobiological, and psychosocial factors is quite likely. The aim of this study is to provide a systematic overview on imaging studies on CDs and investigate neuronal areas involved in Motor Conversion Disorders (MCD).

methodsA systematic literature search was conducted on CD. Subsequently a meta-analysis of functional neuroimaging studies on MCD was implemented using an Activation Likelihood Estimation (ALE). We calculated differences between patients and healthy controls as well as between affected versus unaffected sides in addition to an overall analysis in order to identify neuronal areas related to MCD.

resultsPatients with MCD differ from healthy controls in the amygdala, superior temporal lobe, retrosplenial area, primary motor cortex, insula, red nucleus, thalamus, anterior as well as dorsolateral prefrontal and frontal cortex. When comparing affected versus unaffected sides, temporal cortex, dorsal anterior cingulate cortex, supramarginal gyrus, dorsal temporal lobe, anterior insula, primary somatosensory cortex, superior frontal gyrus and anterior prefrontal as well as frontal cortex show significant differences.

conclusionsNeuronal areas seem to be involved in the pathogenesis, maintenance or as a result of MCD. Areas that are important for motor-planning, motor-selection or autonomic response seem to be especially relevant. Our results support the emotional unawareness theory but also underline the need of more support by conduction imaging studies on both CD and MCD.

Indexed as

BrainConversion DisorderEmotionsHumansMagnetic Resonance ImagingNeuroimagingHysteriaMeta-analysisMotor conversion disorderNeuroimagingNeurology

Identifiers

PMID27283002
PMCPMC4901519
OpenAlexW2415597248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.