Evidence map›Paper›PMID 27282272›Full record

ArticleGut and liver2016

Differences in Clinical Manifestations according to the Positivity of Interferon-γ Assay in Patients with Intestinal Tuberculosis.

Hye Jin Jung, Young-Ho Kim, You Sun Kim, Seong Yeon Jeong, Sung Won Park, Ji Yeon Seo, Hyemi Jung, Jong Pil Im, Ji Won Kim, Sung Noh Hong and 1 more

Open access · diamondAbstract readComparative StudyEvaluation StudyMulticenter Study
In one paragraph

Article in Gut and liver, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Clinicopathological profile of gastrointestinal tuberculosis: a multinational ID-IRI study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hye Jin JungDepartment of Internal Medicine, Inje University College of Medicine, Seoul, Korea.
Young-Ho KimDepartment of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
You Sun KimDepartment of Internal Medicine, Inje University College of Medicine, Seoul, Korea.
Seong Yeon JeongDepartment of Internal Medicine, Inje University College of Medicine, Seoul, Korea.
Sung Won ParkDepartment of Internal Medicine, Inje University College of Medicine, Seoul, Korea.
Ji Yeon SeoDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Hyemi JungDepartment of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jong Pil ImDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ji Won KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Sung Noh HongDepartment of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kuk Lae LeeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Inje University · KRSeoul National University · KRCatholic Kwandong University International St. Mary's Hospital · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal tuberculosis (ITB) remains prevalent in Asia. An interferon-γ assay (QuantiFERON-TB gold test [QFT]) is considered to be an effective supplementary tool for diagnosing ITB. We retrospectively analyzed the clinical features of ITB patients based on the initial results of QFT. A total of 109 patients with ITB were enrolled, and 82 patients (75.2%) showed positive QFT results. In the QFT-positive group, the mean age (44.1±12.0 years) was significantly higher than that in the QFT-negative group (37.0±14.8, p=0.0096). Abdominal pain (p=0.006) and diarrhea (p=0.030) were more frequent in the QFT-negative group. Further, C-reactive protein (CRP) levels were significantly higher in the QFTnegative group (6.4±9.9 mg/dL) than in the QFT-positive group (1.3±2.3, p<0.001). Multivariate analysis confirmed that younger age (p=0.016), diarrhea (p=0.042), and high levels of CRP (p=0.029) were independent predictors of QFTnegative results in patients with ITB. These results suggest that prior exposure to TB, reflected by QFT positivity, may cause mild inflammation in patients with ITB.

Indexed as

Abdominal PainAdultC-Reactive ProteinDiarrheaFemaleHumansInterferon-gammaInterferon-gamma Release TestsMaleRetrospective StudiesTuberculosis, GastrointestinalC-Reactive ProteinInterferon-gammaC-reactive proteinInterferon-gamma assayIntestinal tuberculosis

Identifiers

PMID27282272
PMCPMC4933428
OpenAlexW2412347300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.