Evidence map›Paper›PMID 27282271›Full record

ArticleGut and liver2016

Coordinated Hospital-Home Fecal Microbiota Transplantation via Percutaneous Endoscopic Cecostomy for Recurrent Steroid-Dependent Ulcerative Colitis.

Xiaodong Ni, Shengxian Fan, Yongliang Zhang, Zhiming Wang, Lan Ding, Yousheng Li, Jieshou Li

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Gut and liver, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaodong NiIntestinal Rehabiliton and Transplant Center, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Shengxian FanIntestinal Rehabiliton and Transplant Center, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Yongliang ZhangIntestinal Rehabiliton and Transplant Center, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Zhiming WangIntestinal Rehabiliton and Transplant Center, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Lan DingIntestinal Rehabiliton and Transplant Center, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Yousheng LiIntestinal Rehabiliton and Transplant Center, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Jieshou LiIntestinal Rehabiliton and Transplant Center, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Nanjing University · CNNanjing General Hospital of Nanjing Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its introduction as an alternative intestinal microbiota alteration approach, fecal microbiota transplantation (FMT) has been increasingly used as a treatment of choice for patients with ulcerative colitis (UC), but no reports exist regarding FMT via percutaneous endoscopic cecostomy (PEC). This report describes the case of a 24-year-old man with a 7-year history of recurrent, steroid-dependent UC. He received FMT via PEC once per day for 1 month in the hospital. After the remission of gastrointestinal symptoms, he was discharged from the hospital and continued FMT via PEC twice per week for 3 months at home. The frequency of stools decreased, and the characteristics of stools improved soon thereafter. Enteral nutrition was regained after 1 week, and an oral diet was begun 1 month later. Two months after the FMT end point, the patient resumed a normal diet, with formed soft stools once per day. The follow-up colonoscopy showed normal mucus membranes; then, the PEC set was removed. On the subsequent 12 months follow-up, the patient resumed orthobiosis without any gastrointestinal discomfort and returned to work. This case emphasizes that FMT via PEC can not only induce remission but also shorten the duration of hospitalization and reduce the medical costs; therefore, this approach should be considered an alternative option for patients with UC.

Indexed as

CecostomyColitis, UlcerativeColonoscopyCombined Modality TherapyFecal Microbiota TransplantationHumansMaleRecurrenceSteroidsTreatment OutcomeYoung AdultSteroidsColitis, ulcerativeFecal microbiota transplantationPercutaneous endoscopic cecostomy

Identifiers

PMID27282271
PMCPMC5087939
OpenAlexW2418259152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.