Evidence map›Paper›PMID 27282117›Full record

Trial reportContemporary clinical trials2016

Interim methadone and patient navigation in jail: Rationale and design of a randomized clinical trial.

Robert P Schwartz, Sharon M Kelly, Shannon G Mitchell, Laura Dunlap, Gary A Zarkin, Anjalee Sharma, Kevin E O'Grady, Jerome H Jaffe

Erratum issued Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02334215 (A Randomized Trial of Interim Methadone and Patient Navigation Initiated in Jail), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02334215 nacompletednot on this map

A Randomized Trial of Interim Methadone and Patient Navigation Initiated in Jail

TypeinterventionalSponsorFriends Research Institute, Inc.Ran2014 to 2020Enrolled225ConditionsOpioid Use DisorderArmsMethadone, Patient Navigation, Enhanced Treatment as Usual (ETAU)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Robert P SchwartzFriends Research Institute, Baltimore, MD, USA. Electronic address: rschwartz@friendsresearch.org.
Sharon M KellyFriends Research Institute, Baltimore, MD, USA.
Shannon G MitchellFriends Research Institute, Baltimore, MD, USA.
Laura DunlapRTI International, Research Triangle Park, NC, USA.
Gary A ZarkinRTI International, Research Triangle Park, NC, USA.
Anjalee SharmaFriends Research Institute, Baltimore, MD, USA.
Kevin E O'GradyDepartment of Psychology, University of Maryland, College Park, College Park, MD, USA.
Jerome H JaffeFriends Research Institute, Baltimore, MD, USA; Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

Funding

A Randomized Trial of Interim Methadone and Patient Navigation Initiated in JailU01DA013636 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI SCHWARTZ, ROBERT P · 2013 to 2016
$2.4M
NIDA NIH HHS U01 DA013636
6 · The paper itself

Abstract

backgroundMethadone maintenance is an effective treatment for opioid dependence but is rarely initiated in US jails. Patient navigation is a promising approach to improve continuity of care but has not been tested in bridging the gap between jail- and community-based drug treatment programs.

methodsThis is an open-label randomized clinical trial among 300 adult opioid dependent newly-arrested detainees that will compare three treatment conditions: methadone maintenance without routine counseling (termed Interim Methadone; IM) initiated in jail v. IM and patient navigation v. enhanced treatment-as-usual. The two primary outcomes will be: (1) the rate of entry into treatment for opioid use disorder within 30days from release and (2) frequency of opioid positive urine tests over the 12-month follow-up period. An economic analysis will examine the costs, cost-effectiveness, and cost-benefit ratio of the study interventions.

resultsWe describe the background and rationale for the study, its aims, hypotheses, and study design.

conclusionsGiven the large number of opioid dependent detainees in the US and elsewhere, initiating IM at the time of incarceration could be a significant public health and clinical approach to reducing relapse, recidivism, HIV-risk behavior, and criminal behavior. An economic analysis will be conducted to assist policy makers in determining the utility of adopting this approach. ClinicalTrials.gov: NCT02334215.

Indexed as

Community Health ServicesPrisonsAnalgesics, OpioidCost-Benefit AnalysisCosts and Cost AnalysisFemaleHumansMaleMethadoneOpiate Substitution TreatmentOpioid-Related DisordersPatient NavigationPatient TransferUnited StatesAnalgesics, OpioidMethadoneCriminal justiceInterim methadoneJailMethadone treatmentPatient navigation

Identifiers

PMID27282117
PMCPMC4969178

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.