ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2017
Pulsed electromagnetic field therapy improves tendon-to-bone healing in a rat rotator cuff repair model.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 43 citations in OpenAlex.
- The promising regenerative potential of pulsed electromagnetic fields toward tendon differentiation : a hamstring tendon explant culture study.Bone & joint research · 2026Article
- Active vs. sham pulsed electromagnetic field therapy added to standardized conservative care for partial-thickness supraspinatus tears: study protocol for a randomized, assessor-blinded, sham-controlled trial.Frontiers in sports and active living · 2026Article
- Article
- Dose-independent adverse effects of corticosteroid injections on rotator cuff healing in a rat model.Acta orthopaedica et traumatologica turcica · 2025Article
- Investigation of the efficiency of pulsed electromagnetic field treatment and stretching exercise in experimental skeletal muscle injury model.BMC musculoskeletal disorders · 2025Article
- Review
- Gathering Evidence to Leverage Musculoskeletal Magnetic Stimulation Towards Clinical Applicability.Small science · 2024Article
- Electromagnetic fields regulate calcium-mediated cell fate of stem cells: osteogenesis, chondrogenesis and apoptosis.Stem cell research & therapy · 2023Review
- Effect of uniform capacitively coupled electric fields on matrix metabolism of osteoarthritic cartilage.Bioelectronic medicine · 2022Article
- Pulsed electromagnetic field therapy alters early healing in a rat model of rotator cuff injury and repair: Potential mechanisms.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Regulation of skeletal myogenesis in C2C12 cells through modulation of Pax7, MyoD, and myogenin via different low-frequency electromagnetic field energies.Technology and health care : official journal of the European Society for Engineering and Medicine · 2022Article
- Evaluation of pulsed electromagnetic field protocols in implant osseointegration: in vivo and in vitro study.Clinical oral investigations · 2021Article
- Effects of focused continuous pulsed electromagnetic field therapy on early tendon-to-bone healing.Bone & joint research · 2021Article
- Liquid Poly-N-acetyl Glucosamine (sNAG) Improves Achilles Tendon Healing in a Rat Model.Annals of biomedical engineering · 2021Review
- In Vitro Innovation of Tendon Tissue Engineering Strategies.International journal of molecular sciences · 2020Review
- Pulsed electromagnetic fields improve the healing process of Achilles tendinopathy: a pilot study in a rat model.Bone & joint research · 2020Article
- Magnetic biomaterials and nano-instructive tools as mediators of tendon mechanotransduction.Nanoscale advances · 2020Review
- Effects of Pulsed Electromagnetic Field Therapy on Rat Achilles Tendon Healing.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Article
- Quantitative comparison of three rat models of Achilles tendon injury: A multidisciplinary approach.Journal of biomechanics · 2019Article
- Low‑frequency pulsed electromagnetic field inhibits RANKL‑induced osteoclastic differentiation in RAW264.7 cells by scavenging reactive oxygen species.Molecular medicine reports · 2019Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Rotator cuff tears are common musculoskeletal injuries often requiring surgical intervention with high failure rates. Currently, pulsed electromagnetic fields (PEMFs) are used for treatment of long-bone fracture and lumbar and cervical spine fusion surgery. Clinical studies examining the effects of PEMF on soft tissue healing show promising results. Therefore, we investigated the role of PEMF on rotator cuff healing using a rat rotator cuff repair model. We hypothesized that PEMF exposure following rotator cuff repair would improve tendon mechanical properties, tissue morphology, and alter in vivo joint function. Seventy adult male Sprague-Dawley rats were assigned to three groups: bilateral repair with PEMF (n = 30), bilateral repair followed by cage activity (n = 30), and uninjured control with cage activity (n = 10). Rats in the surgical groups were sacrificed at 4, 8, and 16 weeks. Control group was sacrificed at 8 weeks. Passive joint mechanics and gait analysis were assessed over time. Biomechanical analysis and μCT was performed on left shoulders; histological analysis on right shoulders. Results indicate no differences in passive joint mechanics and ambulation. At 4 weeks the PEMF group had decreased cross-sectional area and increased modulus and maximum stress. At 8 weeks the PEMF group had increased modulus and more rounded cells in the midsubstance. At 16 weeks the PEMF group had improved bone quality. Therefore, results indicate that PEMF improves early tendon healing and does not alter joint function in a rat rotator cuff repair model. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:902-909, 2017.
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