Evidence map›Paper›PMID 27280966›Full record

ArticleJournal of affective disorders2016

Functional domains as correlates of suicidality among psychiatric inpatients.

Zimri S Yaseen, Igor I Galynker, Jessica Briggs, Rachel D Freed, Vilma Gabbay

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Anhedonia and Suicide.Current topics in behavioral neurosciences · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Candidate Biomarkers of Suicide Crisis Syndrome: What to Test Next? A Concept Paper.The international journal of neuropsychopharmacology · 2020
    Review
  12. Review
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zimri S YaseenIcahn School of Medicine at Mount Sinai, Department of Psychiatry, One Gustave L. Levy Place, New York, NY 10029, USA; Mount Sinai Beth Israel, Department of Psychiatry, First Avenue at 16th Street, New York, NY 10003, USA. Electronic address: zsyaseen@gmail.com.
Igor I GalynkerIcahn School of Medicine at Mount Sinai, Department of Psychiatry, One Gustave L. Levy Place, New York, NY 10029, USA; Mount Sinai Beth Israel, Department of Psychiatry, First Avenue at 16th Street, New York, NY 10003, USA.
Jessica BriggsMount Sinai Beth Israel, Department of Psychiatry, First Avenue at 16th Street, New York, NY 10003, USA.
Rachel D FreedIcahn School of Medicine at Mount Sinai, Department of Psychiatry, One Gustave L. Levy Place, New York, NY 10029, USA.
Vilma GabbayIcahn School of Medicine at Mount Sinai, Department of Psychiatry, One Gustave L. Levy Place, New York, NY 10029, USA; Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.
Mount Sinai Beth Israel · USIcahn School of Medicine at Mount Sinai · USNathan Kline Institute for Psychiatric Research · US

Funding

Neuroinflammation and PVS Deficits in AdolescentsR01MH101479 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GABBAY, VILMA · 2014 to 2018
$3.1M
The Neuroimmunology of AnhedoniaR01MH095807 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GABBAY, VILMA · 2012 to 2016
$3.0M
NIMH NIH HHS R01 MH095807NIMH NIH HHS R01 MH101479
6 · The paper itself

Abstract

backgroundSuicide remains poorly understood and unpredictable. Addressing this challenge, this study examined the independent contributions of several research domain criteria (RDoC) constructs in relation to suicidality in patients hospitalized for acute suicide risk. Specifically, we examined anhedonia, anxiety/entrapment, and attachment disturbances, reflecting disturbances in reward processes, negative valence systems, and social processes, respectively.

methodsAnhedonia, anxiety, entrapment, and fearful attachment, were assessed quantitatively in 135 adults hospitalized for suicidality. Current suicidality and suicidal history were assessed with the Columbia Suicide Severity Rating Scale. Bivariate analyses (with significance threshold of p<.01 to account for multiple comparisons) and multivariate models examined relationships between symptom dimensions and severity of suicidal ideation (SI). We also assessed differences between patients with a history of suicide attempt and those who exhibited only suicidal ideations.

resultsUsing bivariate analyses all symptoms except for fearful attachment correlated robustly with SI (r =.37-0.50, p<.001). However, when using multivariate analyses, only anhedonia (β=.28, p=.01) and entrapment (β=.19, p=.03) were independently associated with SI across the entire sample. No functional domain measures differed between patients with history of suicide attempt versus ideation only. LIMITATIONS: The reliance on self-report data and a cross-sectional design.

conclusionsDisturbances in reward and threat processing may represent independent factors in the development of suicidal ideation in this high suicide risk cohort. Future studies should assess their role as risk factors.

Indexed as

AnhedoniaObject AttachmentSuicidal IdeationAdolescentAdultAgedAnxietyCross-Sectional StudiesFearFemaleHumansInpatientsMaleMiddle AgedRisk FactorsSelf ReportAnhedoniaAnxietyAttachmentEntrapmentRDoCSuicide

Identifiers

PMID27280966
PMCPMC4975988
OpenAlexW2416287409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.