ReviewCurrent cardiology reviews
Type 2 Diabetes and Heart Failure: Challenges and Solutions.
Review in Current cardiology reviews. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 117 citations in OpenAlex.
- Efficacy and safety of ertugliflozin in patients with type 2 diabetes mellitus and established cardiovascular disease using insulin: A VERTIS CV substudy.Diabetes, obesity & metabolism · 2021 · on this mapTrial
- SOCIO-CLINICAL DEMOGRAPHICS AND RISK FACTORS FOR HEART FAILURE AT A TERTIARY HOSPITAL IN SOUTH-SOUTH NIGERIA: A CROSS-SECTIONAL STUDY.Annals of Ibadan postgraduate medicine · 2025Article
- Cellular and Molecular Pathways in Diabetes-Associated Heart Failure: Emerging Mechanistic Insights and Therapeutic Opportunities.Current issues in molecular biology · 2025Review
- Alterations in glucocorticoid homeostasis following sleeve gastrectomy.bioRxiv : the preprint server for biology · 2025Article
- T2D-LVDD: neural network-based predictive models for left ventricular diastolic dysfunction in type 2 diabetes.Diabetology & metabolic syndrome · 2025Article
- Correlation between atherogenic index of plasma and cardiovascular disease risk across Cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study.Cardiovascular diabetology · 2025Article
- Remnant Cholesterol Inflammatory Index for Predicting Heart Failure Risk in Patients with Coronary Artery Disease and Type 2 Diabetes: A Retrospective Study Using Multiple Machine Learning Approaches.Risk management and healthcare policy · 2025Article
- Type 2 diabetes mellitus negatively affects the functional performance of 6-min step test in chronic heart failure: a 3-year follow-up study.Diabetology & metabolic syndrome · 2024Article
- Morin Ameliorates Myocardial Injury in Diabetic Rats via Modulation of Autophagy, Apoptosis, Inflammation, and Oxidative Stress.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Prevalence of anemia and associated All-Cause mortality among adults with Diabetes: The role of chronic kidney disease.Diabetes research and clinical practice · 2023Article
- Contribution of skeletal muscle-specific microRNA-133b to insulin resistance in heart failure.American journal of physiology. Heart and circulatory physiology · 2023Article
- Diabetes mellitus status modifies the association between N-terminal B-type natriuretic peptide and all-cause mortality risk in ischemic heart failure: a prospective cohort study.Diabetology & metabolic syndrome · 2023Article
- Correlation of asprosin and Nrg-4 with type 2 diabetes Mellitus Complicated with Coronary Heart Disease and the Diagnostic Value.BMC endocrine disorders · 2023Article
- Diabetes Mellitus and Heart Failure: Epidemiology, Pathophysiologic Mechanisms, and the Role of SGLT2 Inhibitors.Life (Basel, Switzerland) · 2023Review
- The Involvement of Krüppel-like Factors in Cardiovascular Diseases.Life (Basel, Switzerland) · 2023Review
- Impact of hypoglycemia at the time of hospitalization for heart failure from emergency department on major adverse cardiovascular events in patients with and without type 2 diabetes.Cardiovascular diabetology · 2022Article
- Review
- Impact of diabetes and on-arrival hyperglycemia on short-term outcomes in acute heart failure patients.Internal and emergency medicine · 2022Article
- Elevated Serum Retinol Binding Protein 4 is Associated with the Risk of Diabetic Cardiomyopathy.Reviews in cardiovascular medicine · 2022Article
- Diabetes and treatment of chronic heart failure in a large real-world heart failure population.ESC heart failure · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing numbers of older patients with type 2 diabetes, and their improved survival from cardiovascular events is seeing a massive increase in patients with both diabetes and heart failure. Already, at least a third of all patients with heart failure have diabetes. This close association is partly because all the major risk factors for heart failure also cluster in patients with type 2 diabetes, including obesity, hypertension, advanced age, sleep apnoea, dyslipidaemia, anaemia, chronic kidney disease, and coronary heart disease. However, diabetes may also cause cardiac dysfunction in the absence of overt macrovascular disease, as well as complicate the response to therapy. Current management is focused on targeting modifiable risk factors for heart failure including hyperglycaemia, dyslipidaemia, hypertension, obesity and anemia. But although these are important risk markers, none of these interventions substantially prevents heart failure or improves its outcomes. Much more needs to be done to focus on this issue, including the inclusion of hospital admission for heart failure as a pre-specified component of the primary composite cardiovascular outcomes and new trials in heart failure management specifically in the context of diabetes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.