ArticleCMAJ open
Postpartum domperidone use in British Columbia: a retrospective cohort study.
Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- SUpporting Mothers Milk Intervention Trial (SUMMIT) - a randomised controlled trial comparing different doses of domperidone for treating lactation insufficiency in mothers of preterm infants - study protocol.International breastfeeding journal · 2026Article
- A Survey of U.S. and Canadian Physicians' Clinical Practices Related to Pharmacologic, Herbal, and Nutritional Substances Used to Increase Milk Production.Clinical lactation (Amarillo, Tex.) · 2024Article
- Longitudinal trends in domperidone dispensing to mothers of very preterm infants and its association with breast milk feeding at infant discharge: a retrospective study.BMJ paediatrics open · 2023Article
- Women's experiences with using domperidone as a galactagogue to increase breast milk supply: an australian cross-sectional survey.International breastfeeding journal · 2023Article
- Prevalence of Mental Health Disorders Among Immigrant, Refugee, and Nonimmigrant Children and Youth in British Columbia, Canada.JAMA network open · 2022Article
- "Fear of stopping" vs "wanting to get off the medication": exploring women's experiences of using domperidone as a galactagogue - a qualitative study.International breastfeeding journal · 2021Article
- Article
- The risk-risk trade-offs: Understanding factors that influence women's decision to use substances to boost breast milk supply.PloS one · 2021Article
- What Evidence Do We Have for Pharmaceutical Galactagogues in the Treatment of Lactation Insufficiency?-A Narrative Review.Nutrients · 2019Review
- Supporting Mothers of Very Preterm Infants and Breast Milk Production: A Review of the Role of Galactogogues.Nutrients · 2018Review
- Viewpoint: Domperidone and breastfeeding.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017Article
- Maternal experiences with and sources of information on galactagogues to support lactation: a cross-sectional study.International journal of women's health · 2017Article
- Observational
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundDomperidone is commonly used off-label to stimulate milk production in mothers who have low milk supply. The aim of this study was to describe trends, patterns and determinants of postpartum domperidone use.
methodsThis is a retrospective, population-based study involving all women with a live birth between Jan. 1, 2002, and Dec. 31, 2011, in the province of British Columbia. We examined administrative data sets containing person-specific information on filled prescriptions and use of medical services, and we used logistic regression to examine associations between domperidone use and maternal characteristics.
resultsThe study population consisted of 225 532 women with 320 351 live births. The prevalence of postpartum domperidone use more than doubled between 2002 and 2011. In 2011, 1 in 3 women with a preterm birth and 1 in 5 women with a full-term birth were prescribed domperidone in the first 6 months postpartum. Women who were older, had a higher body mass index, had a chronic disease, were first-time mothers, delivered more than 1 baby (multiple pregnancy), had a preterm birth or had a cesarian delivery were more likely to fill a postpartum domperidone prescription.
interpretationWe found an increase in postpartum domperidone use over a 10-year period. More research is needed on maternal and infant health outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.