ArticleBiomicrofluidics2016
Microfluidics made easy: A robust low-cost constant pressure flow controller for engineers and cell biologists.
Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Hemadyne: accordion-inspired perfusion for microphysiological systems.Nature communications · 2026Article
- Characterizing Recent PDMS Changes in Electrokinetic-Based Microfluidic Devices' Performance and Manufacturing for Cell Sorting Applications.Electrophoresis · 2025Article
- Bioengineered articular cartilage biomimetic organ-on-a-chip using microfluidics.npj biomedical innovations · 2025Article
- Microscale Flow Control and Droplet Generation Using Arduino-Based Pneumatically-Controlled Microfluidic Device.Biosensors · 2024Article
- Self-Sustaining Water Microdroplet Resonators Using 3D-Printed Microfluidics.Micromachines · 2024Article
- Article
- Open-source pneumatic pressure pump for drop-based microfluidic flow controls.Engineering research express · 2023Article
- Review
- Microfluidic Systems For Manufacturing of Microparticle-Based Drug-Delivery Systems: Design, Construction, and Operation.ACS biomaterials science & engineering · 2022Article
- A miniaturized 3D printed pressure regulator (µPR) for microfluidic cell culture applications.Scientific reports · 2022Article
- Integrative lymph node-mimicking models created with biomaterials and computational tools to study the immune system.Materials today. Bio · 2022Review
- An "occlusive thrombosis-on-a-chip" microfluidic device for investigating the effect of anti-thrombotic drugs.Lab on a chip · 2021Article
- Simultaneous Droplet Generation with In-Series Droplet T-Junctions Induced by Gravity-Induced Flow.Micromachines · 2021Article
- An Arduino-based constant pressure fluid pump.The European physical journal. E, Soft matter · 2021Article
- Distributed colorimetric interferometer for mapping the pressure distribution in a complex microfluidics network.Lab on a chip · 2021Article
- Passive micropumping in microfluidics for point-of-care testing.Biomicrofluidics · 2020Review
- Flattening of Diluted Species Profile via Passive Geometry in a Microfluidic Device.Micromachines · 2019Article
- A flow-based microfluidic device for spatially quantifying intracellular calcium ion activity during cellular electrotaxis.Biomicrofluidics · 2019Article
- A System for Analog Control of Cell Culture Dynamics to Reveal Capabilities of Signaling Networks.iScience · 2019Article
- Microfluidics on the fly: Inexpensive rapid fabrication of thermally laminated microfluidic devices for live imaging and multimodal perturbations of multicellular systems.Biomicrofluidics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last decade, microfluidics has become increasingly popular in biology and bioengineering. While lab-on-a-chip fabrication costs have continued to decrease, the hardware required for delivering controllable fluid flows to the microfluidic devices themselves remains expensive and often cost prohibitive for researchers interested in starting a microfluidics project. Typically, microfluidic experiments require precise and tunable flow rates from a system that is simple to operate. While many labs use commercial platforms or syringe pumps, these solutions can cost thousands of dollars and can be cost prohibitive. Here, we present an inexpensive and easy-to-use constant pressure system for delivering flows to microfluidic devices. The controller costs less than half the price of a single syringe pump but can independently switch and deliver fluid through up to four separate fluidic inlets at known flow rates with significantly faster fluid response times. It is constructed of readily available pressure regulators, gauges, plastic connectors and adapters, and tubing. Flow rate is easily predicted and calibrated using hydraulic circuit analysis and capillary tubing resistors. Finally, we demonstrate the capabilities of the flow system by performing well-known microfluidic experiments for chemical gradient generation and emulsion droplet production.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.