ArticleClinical interventions in aging2016
Factors associated with postoperative complications and 1-year mortality after surgery for colorectal cancer in octogenarians and nonagenarians.
Article in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 55 citations in OpenAlex.
- Self-Expandable Metal Stent as a Bridge to Surgery for Left-Sided Acute Malignant Colorectal Obstruction: Optimal Timing for Elective Surgery.Computational and mathematical methods in medicine · 2022Trial
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- Safety and feasibility of D3 lymph node dissection in oldest-old patients undergoing colorectal cancer surgery: a multi-institutional, retrospective analysis.Techniques in coloproctology · 2025Article
- Impact of Preoperative and Intraoperative Factors on Postoperative Outcomes in Patients with Colorectal Cancer: A 10-Year Retrospective Study.Diseases (Basel, Switzerland) · 2025Article
- Nutritional intervention during a teleprehabilitation pilot study in high-risk patients with colorectal cancer: adherence, motivators, and barriers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Correlation between spleen density and prognostic outcomes in patients with colorectal cancer after curative resection.BMC cancer · 2024Article
- Perioperative outcome, long-term mortality and time trends in elderly patients undergoing low-, intermediate- or major non-cardiac surgery.Aging clinical and experimental research · 2024Observational
- Presentation, Molecular Characteristics, Treatment, and Outcomes of Colorectal Cancer in Patients Older than 80 Years Old.Medicina (Kaunas, Lithuania) · 2023Review
- Mortality and morbidity following operative management of tibial shaft fractures in octogenarians.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Disproportionately high failure to rescue rates after resection for colorectal cancer in the geriatric patient population - A nationwide study.Cancer medicine · 2022Article
- Article
- Oxidative Stress Predicts Post-Surgery Complications in Gastrointestinal Cancer Patients.Annals of surgical oncology · 2022Article
- Colorectal cancer surgery in elderly patients 80 years and older: a comparison with younger age groups.Journal of gastrointestinal oncology · 2022Article
- External validation of a risk model for survival prediction in older patients with cancer undergoing elective abdominal surgery: a prospective cohort study.American journal of cancer research · 2022Article
- Short and long-term outcomes of elderly patients undergoing left-sided colorectal resection with primary anastomosis for cancer.BMC geriatrics · 2021Article
- Morbidity and Mortality After Surgical Management of Tibial Plateau Fractures in Octogenarians.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2021Article
- Risk scores to predict mortality 2 and 5 years after surgery for colorectal cancer in elderly patients.World journal of surgical oncology · 2021Observational
- Psoas Muscle Index Defined by Computer Tomography Predicts the Presence of Postoperative Complications in Colorectal Cancer Surgery.Medicina (Kaunas, Lithuania) · 2021Article
- Impact of laparoscopic approach on the short-term outcomes of elderly patients with colorectal cancer: a nationwide Italian experience.Surgical endoscopy · 2020Observational
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Authors and funding
2 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo identify the factors affecting 30-day postoperative complications and 1-year mortality after surgery for colorectal cancer in octogenarians and nonagenarians.
methodsBetween 2005 and 2014, a total of 204 consecutive patients aged ≥80 years who underwent major colorectal surgery were included.
resultsOne hundred patients were male (49%) and 52 patients had American Society of Anesthesiologists (ASA) score ≥3 (25%). Combined surgery was performed in 32 patients (16%). Postoperative complications within 30 days after surgery occurred in 54 patients (26%) and 30-day mortality occurred in five patients (2%). Independent risk factors affecting 30-day postoperative complications were older age (≥90 years, hazard ratio [HR] with 95% confidence interval [CI] =4.95 [1.69-14.47], P=0.004), an ASA score ≥3 (HR with 95% CI =4.19 [1.8-9.74], P=0.001), performance of combined surgery (HR with 95% CI =3.1 [1.13-8.46], P=0.028), lower hemoglobin level (<10 g/dL, HR with 95% CI =7.56 [3.07-18.63], P<0.001), and lower albumin level (<3.4 g/dL, HR with 95% CI =3.72 [1.43-9.69], P=0.007). An ASA score ≥3 (HR with 95% CI =2.72 [1.15-6.46], P=0.023), tumor-node-metastasis (TNM) stage IV (HR with 95% CI =3.47 [1.44-8.39], P=0.006), and occurrence of postoperative complications (HR with 95% CI =4.42 [1.39-14.09], P=0.012) were significant prognostic factors for 1-year mortality.
conclusionPatient-related factors (older age, higher ASA score, presence of anemia, and lower serum albumin) and procedure-related factors (performance of combined surgical procedure) increased postoperative complications. Avoidance of 30-day postoperative complications may decrease 1-year mortality.
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