ArticleMagnetic resonance in medicine2017
Quantitative and textural analysis of magnetization transfer and diffusion images in the early detection of brain metastases.
Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brain metastasis detection using machine learning: a systematic review and meta-analysis.Neuro-oncology · 2021Pooled it
- Unsupervised anomaly detection for tumor delineation in a preclinical model of glioblastoma using CEST MRI.bioRxiv : the preprint server for biology · 2026Article
- The application of radiomics in predicting gene mutations in cancer.European radiology · 2022Review
- Radiomics analysis of lung CT image for the early detection of metastases in patients with breast cancer: preliminary findings from a retrospective cohort study.European radiology · 2020Article
- Brain metastases from lung cancer with neuropsychiatric symptoms as the first symptoms.Translational lung cancer research · 2019Article
- MRI based texture analysis to classify low grade gliomas into astrocytoma and 1p/19q codeleted oligodendroglioma.Magnetic resonance imaging · 2019Article
- Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.International journal of molecular sciences · 2019Review
- Advanced Magnetic Resonance Imaging Techniques in Management of Brain Metastases.Frontiers in oncology · 2019Review
- Predicting brain metastases for non-small cell lung cancer based on magnetic resonance imaging.Clinical & experimental metastasis · 2017Article
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Authors and funding
7 authors.
Funding
Abstract
purposeThe sensitivity of the magnetization transfer ratio (MTR) and apparent diffusion coefficient (ADC) for early detection of brain metastases was investigated in mice and humans.
methodsMice underwent MRI twice weekly for up to 31 d following intracardiac injection of the brain-homing breast cancer cell line MDA-MB231-BR. Patients with small cell lung cancer underwent quarterly MRI for 1 year. MTR and ADC were measured in regions of metastasis and matched contralateral tissue at the final time point and in registered regions at earlier time points. Texture analysis and linear discriminant analysis were performed to detect metastasis-containing slices.
resultsCompared with contralateral tissue, mouse metastases had significantly lower MTR and higher ADC at the final time point. Some lesions were visible at earlier time points on the MTR and ADC maps: 24% of these were not visible on corresponding T
conclusionsSome brain metastases may be detected earlier on MTR than conventional T
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