Evidence map›Paper›PMID 27279132›Full record

ArticleJournal of veterinary internal medicine2016

Treatment of MRI-Diagnosed Trigeminal Peripheral Nerve Sheath Tumors by Stereotactic Radiotherapy in Dogs.

K S Hansen, A L Zwingenberger, A P Théon, I Pfeiffer, M S Kent

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  8. Review
  9. Article
  10. A survey of stereotactic radiation therapy in veterinary medicine.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2018
    Article
  11. Consensus recommendations on standardized magnetic resonance imaging protocols for multicenter canine brain tumor clinical trials.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2018
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

K S HansenDepartment of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, Davis, CA.
A L ZwingenbergerDepartment of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, Davis, CA.
A P ThéonDepartment of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, Davis, CA.
I PfeifferDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN.
M S KentDepartment of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, Davis, CA.
University of California, Davis · USUniversity of Tennessee at Knoxville · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura Marcu · 2002 to 2026
$84.9M
NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

backgroundStereotactic radiotherapy (SRT) is an emerging technique for treating tumors in animals.

objectivesTo assess the outcome of dogs with suspected intracranial trigeminal nerve peripheral nerve sheath tumors (PNST) treated with SRT. ANIMALS: Eight dogs with presumptive PNST.

methodsThis was a retrospective study of dogs identified by searching UC Davis Veterinary Medical Teaching Hospital medical records for dogs treated with SRT for a presumed PNST. Presumptive diagnosis was based on magnetic resonance imaging. SRT was delivered in 3 dose fractions of 8 Gray (Gy) on consecutive days or every other day to a total dose of 24 Gy.

resultsMedian disease-specific survival was 745 days (range: 99-1375 days, n = 6). No signs of acute adverse effects of radiation treatment were recorded. Late radiation effects versus tumor progression could not be confirmed histopathologically because of few animals undergoing necropsy. CONCLUSIONS AND CLINICAL IMPORTANCE: This study provides preliminary evidence that dogs with PNST benefit from SRT in terms of long-term survival. The treatment appears to be well tolerated and requires fewer anesthetic events for animals compared to full-course radiation.

Indexed as

AnimalsDisease-Free SurvivalDog DiseasesDogsFemaleMagnetic Resonance ImagingMaleMedical RecordsNeurilemmomaRetrospective StudiesStereotaxic TechniquesTreatment OutcomeTrigeminal Nerve DiseasesRadiationStereotactic radiosurgeryStereotactic radiotherapyTrigeminalVeterinary

Identifiers

PMID27279132
PMCPMC5089643
OpenAlexW2414158875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.