Evidence map›Paper›PMID 27279085›Full record

ArticleInvertebrate neuroscience : IN2016

Studies on regeneration of central nervous system and social ability of the earthworm Eudrilus eugeniae.

Nino Gopi Daisy, Elaiya Raja Subramanian, Jackson Durairaj Selvan Christyraj, Dinesh Kumar Sudalai Mani, Johnson Retnaraj Samuel Selvan Christyraj, Kalidas Ramamoorthy, Vaithilingaraja Arumugaswami, Sudhakar Sivasubramaniam

Abstract read
PubMed Publisher
In one paragraph

Article in Invertebrate neuroscience : IN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nino Gopi DaisyDepartment of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Elaiya Raja SubramanianDepartment of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Jackson Durairaj Selvan ChristyrajDepartment of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Dinesh Kumar Sudalai ManiDepartment of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Johnson Retnaraj Samuel Selvan ChristyrajCenter for Nanoscience and Nanotechnology, Molecular Nanomedicine Research Unit, Sathyabama University, Chennai, Tamilnadu, 600119, India.
Kalidas RamamoorthyDepartment of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Vaithilingaraja ArumugaswamiBoard of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Sudhakar SivasubramaniamDepartment of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India. sudhakarmsu@yahoo.com.
Manonmaniam Sundaranar University · INUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Earthworms are segmented invertebrates that belong to the phylum Annelida. The segments can be divided into the anterior, clitellar and posterior parts. If the anterior part of the earthworm, which includes the brain, is amputated, the worm would essentially survive even in the absence of the brain. In these brain amputee-derived worms, the nerve cord serves as the primary control center for neurological function. In this current work, we studied changes in the expression levels of anti-acetylated tubulin and serotonin as the indicators of neuro-regenerative processes. The data reveal that the blastemal tissues express the acetylated tubulin and serotonin from day four and that the worm amputated at the 7th segment takes 30 days to complete the regeneration of brain. The ability of self-assemblage is one of the specific functions of the earthworm's brain. The brain amputee restored the ability of self-assemblage on the eighth day.

Indexed as

Social BehaviorAnimalsCentral Nervous SystemOligochaetaRegenerationBrainEudrilus eugeniaeRegenerationSelf-assemblageSerotoninSocial behavior

Identifiers

PMID27279085
OpenAlexW2418899875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.