Evidence map›Paper›PMID 27279083›Full record

Trial reportDiabetic medicine : a journal of the British Diabetic Association2017

Baseline characteristics of participants in the Kerala Diabetes Prevention Program: a cluster randomized controlled trial of lifestyle intervention in Asian Indians.

T Sathish, B Oldenburg, R J Tapp, J E Shaw, R Wolfe, B Sajitha, F D'Esposito, P Absetz, E Mathews, P Z Zimmet and 1 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetic medicine : a journal of the British Diabetic Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

T SathishMelbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
B OldenburgMelbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
R J TappMelbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
J E ShawBaker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.
R WolfeDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
B SajithaAchutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
F D'EspositoMelbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
P AbsetzSchool of Health Sciences, University of Tampere, Tampere, Finland.
E MathewsAchutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
P Z ZimmetBaker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.
K R ThankappanAchutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Sree Chitra Thirunal Institute for Medical Sciences and Technology · INUniversity of Melbourne · AUBaker Heart and Diabetes Institute · AUCollaborative Care Systems Finland · FIMonash University · AUSingapore National Eye Center · SG

Funding

Building the Asian NCoD Research Network for Regional Research CapacityD43TW008332 · FIC · MONASH UNIVERSITY · PI FISHER, EDWIN B, KADIR, KHALID · 2010 to 2014
$1.0M
FIC NIH HHS D43 TW008332
6 · The paper itself

Abstract

aimsTo describe the baseline characteristics of participants in the Kerala Diabetes Prevention Program.

methodsThe Kerala Diabetes Prevention Program is a cluster randomized controlled trial of lifestyle intervention for prevention of Type 2 diabetes mellitus in India. Participants in the study were those aged 30-60 years who had an Indian Diabetes Risk Score ≥ 60 and who were without Type 2 diabetes on oral glucose tolerance test. Data on demographic, lifestyle, clinical and biochemical characteristics were collected using standardized tools.

resultsA total of 2586 individuals were screened with the Indian Diabetes Risk Score, of these 1529 people (59.1%) had a score ≥ 60, of whom 1209 (79.1%) underwent an oral glucose tolerance test. A total of 202 individuals (16.7%) had undiagnosed Type 2 diabetes and were excluded, and the remaining 1007 individuals were enrolled in the trial (control arm, n = 507; intervention arm, n = 500). The mean participant age was 46.0 ± 7.5 years, and 47.2% were women. The mean Indian Diabetes Risk Score was 67.1 ± 8.4. More than two-thirds (69.0%) had prediabetes and 31.0% had normal glucose tolerance. The prevalence of cardiometabolic risk factors was high, including current tobacco use (34.4% in men), current alcohol use (39.3% in men), no leisure time exercise (98.0%), no daily intake of fruit and vegetables (78.7%), family history of diabetes (47.9%), overweight or obesity (68.5%), hypertension (22.3%) and dyslipidemia (85.4%).

conclusionsThe Kerala Diabetes Prevention Program recruited participants using a diabetes risk score. A large proportion of the participants had prediabetes and there were high rates of cardiometabolic risk factors. The trial will evaluate the effectiveness of lifestyle intervention in a population selected on the basis of a diabetes risk score.

Indexed as

Risk Reduction BehaviorAdultAsian PeopleDiabetes Mellitus, Type 2FemaleHumansIndiaLife StyleMaleMiddle AgedPatient Education as TopicPrediabetic StatePrimary Prevention

Identifiers

PMID27279083
PMCPMC5148720
OpenAlexW2409869537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.