ArticleDigestive diseases and sciences2016
Colorectal Cancer in Young African Americans: Is It Time to Revisit Guidelines and Prevention?
Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- A systematic review of methods to estimate colorectal cancer incidence using population-based cancer registries.BMC medical research methodology · 2022Pooled it
- Statistical methods for measuring trends in colorectal cancer incidence in registries: A systematic review.Frontiers in oncology · 2022Pooled it
- Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer.The American journal of gastroenterology · 2017Guideline
- Early and late-onset colorectal cancer in African Americans during COVID-19.World journal of gastrointestinal oncology · 2025Article
- Identifying distinct prognostic and predictive contributions of tumor epithelium versus tumor microenvironment in colorectal cancer.BMC cancer · 2025Article
- Trends and Symptoms Among Increasing Proportion of African Americans with Early-Onset Colorectal Cancer over a 60-Year Period.Digestive diseases and sciences · 2025Article
- Clinical presentation, treatment patterns, and outcomes of colorectal cancer patients at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia: A prospective cohort study.Cancer reports (Hoboken, N.J.) · 2023Article
- Evaluation of health behaviors and overall quality of life in younger adult African American cancer survivors.Cancer medicine · 2023Article
- Overall Survival Differences in Young Black Colorectal Cancer Patients: a Report from the National Cancer Database.Journal of Cancer · 2023Article
- Article
- Commencing colorectal cancer screening at age 45 years in U.S. racial groups.Frontiers in oncology · 2022Article
- Gut microbiome and its role in colorectal cancer.BMC cancer · 2021Review
- Article
- Racial Disparities in Treatment for Rectal Cancer at Minority-Serving Hospitals.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Racial and ethnic disparities in colorectal cancer incidence and mortality.Advances in cancer research · 2021Article
- Aggressive Colorectal Cancer in the Young.Clinics in colon and rectal surgery · 2020Review
- Afro-Caribbeans Have a Lower Prevalence of Advanced Colon Neoplasia than African-Americans.Digestive diseases and sciences · 2020Article
- Updated Assessment of Colorectal Cancer Incidence in the U.S. by Age, Sex, and Race/Ethnicity.Digestive diseases and sciences · 2020Article
- Causes of Socioeconomic Disparities in Colorectal Cancer and Intervention Framework and Strategies.Gastroenterology · 2020Review
- Examining factors underlying geographic disparities in early-onset colorectal cancer survival among men in the United States.American journal of cancer research · 2020Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND &
aimsPrevious studies have suggested an increase in the incidence of colorectal cancer (CRC) in young adults (younger than 50 years). Among older people, African Americans have disproportionally higher CRC incidence and mortality. We assessed whether this CRC disparity also applies to CRC diagnosed among young people.
methodsUsing the Surveillance, Epidemiology, and End Results cancer registries, a population-based cancer registry covering 25.6 % of the United States' African American population, we identified patients diagnosed with CRC between the years of 2000-2012. The age-adjusted rates for non-Hispanic whites (NHW), African Americans, and Asian-Pacific Islanders (API) were calculated for the age categories 20-24, 25-29, 30-34, 35-39, and 40-44.
resultsCRC age-adjusted incidence is increasing among all three racial groups and was higher for African Americans compared to NHW and API across all years 2000-2012 (P < 0.001). Stage IV CRC was higher in African Americans compared with NHW, while there was higher stage III CRC in API compared with NHWs.
conclusionCRC incidence is increasing among the young in all racial groups under study. This increase in frequency of CRC is true among young African American adults who display highly advanced tumors in comparison with other races. While the present attention to screening seems to have decreased CRC prevalence in individuals older than 50, special attention needs to be addressed to young African American adults as well, to counter the observed trend, as they have the highest incidence of CRC among young population groups by race/ethnicity.
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