ArticleScientific reports2016
Lens-based wavefront sensorless adaptive optics swept source OCT.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 51 citations in OpenAlex.
- Wavenumber-space wavefront sensorless adaptive-optics for optical coherence tomography.Biomedical optics express · 2026Article
- Wide-field cellular-resolution retinal imaging using deformable mirror-based sensorless adaptive optics time-domain full-field OCT.Biomedical optics express · 2025Article
- Deep reinforcement learning for automatic defocus correction using OCT image intensity.Biomedical optics express · 2025Article
- Clinical Application of Adaptive Optics Imaging in Diagnosis, Management, and Monitoring of Ophthalmological Diseases: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
- Multi-modal and multi-scale clinical retinal imaging system with pupil and retinal tracking.Scientific reports · 2022Article
- Optical Coherence Tomography and Glaucoma.Annual review of vision science · 2021Review
- Reflective mirror-based line-scan adaptive optics OCT for imaging retinal structure and function.Biomedical optics express · 2021Article
- High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source.Biomedical optics express · 2021Article
- Discovery and clinical translation of novel glaucoma biomarkers.Progress in retinal and eye research · 2021Review
- Adaptive optics: principles and applications in ophthalmology.Eye (London, England) · 2021Review
- High-speed adaptive optics line-scan OCT for cellular-resolution optoretinography.Biomedical optics express · 2020Article
- Multi-scale and -contrast sensorless adaptive optics optical coherence tomography.Quantitative imaging in medicine and surgery · 2019Article
- Automated sensorless single-shot closed-loop adaptive optics microscopy with feedback from computational adaptive optics.Optics express · 2019Article
- Adaptive optics imaging of the human retina.Progress in retinal and eye research · 2019Review
- Trans-retinal cellular imaging with multimodal adaptive optics.Biomedical optics express · 2018Article
- Enhancement of morphological and vascular features in OCT images using a modified Bayesian residual transform.Biomedical optics express · 2018Article
- Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye.Biomedical optics express · 2018Article
- Roadmap on optical sensors.Journal of optics (2010) · 2017Article
- Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging [Invited].Biomedical optics express · 2017Review
- Wavefront sensorless adaptive optics OCT with the DONE algorithm forBiomedical optics express · 2017Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
Optical coherence tomography (OCT) has revolutionized modern ophthalmology, providing depth resolved images of the retinal layers in a system that is suited to a clinical environment. Although the axial resolution of OCT system, which is a function of the light source bandwidth, is sufficient to resolve retinal features at a micrometer scale, the lateral resolution is dependent on the delivery optics and is limited by ocular aberrations. Through the combination of wavefront sensorless adaptive optics and the use of dual deformable transmissive optical elements, we present a compact lens-based OCT system at an imaging wavelength of 1060 nm for high resolution retinal imaging. We utilized a commercially available variable focal length lens to correct for a wide range of defocus commonly found in patient's eyes, and a novel multi-actuator adaptive lens for aberration correction to achieve near diffraction limited imaging performance at the retina. With a parallel processing computational platform, high resolution cross-sectional and en face retinal image acquisition and display was performed in real time. In order to demonstrate the system functionality and clinical utility, we present images of the photoreceptor cone mosaic and other retinal layers acquired in vivo from research subjects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.