Evidence map›Paper›PMID 27278547›Full record

ArticleAIDS and behavior2017

Use of Western Neuropsychological Test Battery in Detecting HIV-Associated Neurocognitive Disorders (HAND) in Zambia.

Norma Kabuba, J Anitha Menon, Donald R Franklin, Robert K Heaton, Knut A Hestad

Abstract read
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In one paragraph

Article in AIDS and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Norma KabubaDepartment of Psychology, The University of Zambia, Great East Road Campus, P.O BOX 32379, Lusaka, Zambia. zewelanjik@gmail.com.
J Anitha MenonDepartment of Psychology, The University of Zambia, Great East Road Campus, P.O BOX 32379, Lusaka, Zambia.
Donald R FranklinDepartment of Psychiatry, University of California, San Diego, San Diego, CA, USA.
Robert K HeatonDepartment of Psychiatry, University of California, San Diego, San Diego, CA, USA.
Knut A HestadDepartment of Psychology, The Norwegian University of Science and Technology, Trondheim, Norway.

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAVID J MOORE · 2001 to 2026
$50.4M
NIMH NIH HHS P30 MH062512
6 · The paper itself

Abstract

This is a study of neuroAIDS in sub-Saharan Africa, involving 266 Zambian adults infected with the human immunodeficiency virus (HIV), clade C. All HIV+ participants were receiving combination antiretroviral therapy (CART), and were administered a comprehensive neuropsychological (NP) test battery covering seven ability domains that are frequently affected by neuroAIDS. The battery was developed in the U.S. but has been validated in other international settings and has demographically-corrected normative standards based upon 324 healthy Zambian adults. Compared to the healthy Zambian controls, the HIV+ sample performed worse on the NP battery with a medium effect size (Cohen's d = 0.64). 34.6 % of the HIV+ individuals had global NP impairment and met criteria for HIV associated neurocognitive disorder (HAND). The results indicate that the Western-developed NP test battery is appropriate for use in Zambia and can serve as a viable HIV and AIDS management tool.

Indexed as

AdultAfrica South of the SaharaAIDS Dementia ComplexCognition DisordersFemaleHIV InfectionsHumansMaleNeurocognitive DisordersNeuropsychological TestsZambiaHANDHIVNeuropsychological performanceZambia

Identifiers

PMID27278547
PMCPMC5145764

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.