Evidence map›Paper›PMID 27278474›Full record

Trial reportTrials2016

Recruitment of young adults for weight gain prevention: randomized comparison of direct mail strategies.

Melissa M Crane, Jessica Gokee LaRose, Mark A Espeland, Rena R Wing, Deborah F Tate

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01183689 (Study of Novel Approaches for Prevention), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01183689 nacompletednot on this map

Study of Novel Approaches for Prevention

TypeinterventionalSponsorWake Forest UniversityRan2010 to 2018Enrolled599ConditionsWeight GainArmsSmall Behavior Changes, Large Behavior Changes
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Strategies to improve recruitment to randomised trials.The Cochrane database of systematic reviews · 2026
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  8. Randomized trial comparing group size of periodic in-person sessions in a remotely delivered weight loss intervention.The international journal of behavioral nutrition and physical activity · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melissa M CraneGillings School of Global Public Health, University of North Carolina Chapel Hill, Rosenau Hall, Box 7440, Chapel Hill, NC, 27599-7440, USA. mcrane@umn.edu.
Jessica Gokee LaRoseVirginia Commonwealth University, School of Medicine, One Capitol Square, 9th floor, Richmond, VA, 23298, USA.
Mark A EspelandWake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
Rena R WingThe Miriam Hospital/Weight Control and Diabetes Research Center, 196 Richmond Street, Providence, RI, 02903, USA.
Deborah F TateGillings School of Global Public Health, University of North Carolina Chapel Hill, Rosenau Hall, Box 7440, Chapel Hill, NC, 27599-7440, USA.

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Prevention of Weight Gain in Young AdultsU01HL090864 · NHLBI · MIRIAM HOSPITAL · PI WING, RENA R · 2009 to 2014
$5.8M
Minnesota Obesity Prevention Training (MnOPT)T32DK083250 · NIDDK · UNIVERSITY OF MINNESOTA · PI KOTZ, CATHERINE M, LASKA, MELISSA N. · 2010 to 2024
$5.1M
Study of Novel Approaches to Weight Gain Prevention - Extension (SNAP-E)R01HL127341 · NHLBI · MIRIAM HOSPITAL · PI ESPELAND, MARK ANDREW, TATE, DEBORAH F. · 2015 to 2018
$2.9M
Prevention of Weight Gain in Young AdultsU01HL090875 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ESPELAND, MARK ANDREW · 2009 to 2014
$2.0M
NHLBI NIH HHS R01 HL127341NHLBI NIH HHS U01 HL090864NHLBI NIH HHS U01 HL090875NICHD NIH HHS R24 HD050924NIDDK NIH HHS P30 DK056350NIDDK NIH HHS T32 DK083250
6 · The paper itself

Abstract

backgroundRecruiting young adults (ages 18-35 years) into weight gain prevention intervention studies is challenging and men are particularly difficult to reach. This paper describes two studies designed to improve recruitment for a randomized trial of weight gain prevention interventions. Study 1 used a quasi-experimental design to test the effect of two types of direct mailings on their overall reach. Study 2 used a randomized design to test the effect of using targeted messages to increase recruitment of men into the trial.

methodsFor Study 1, 60,000 male and female young-adult households were randomly assigned to receive either a recruitment brochure or postcard. Visits to recruitment websites during each mailing period were used to assess response to each mailing. Study 2 focused on postcard recruitment only. These households received either a targeted or generic recruitment postcard, where targeted postcards included the word "Men" in the headline text. Response rates to each type of card were categorized based on participant report of mailing received.

resultsThe reach of the postcards and brochures were similar (421 and 386 website visits, respectively; P = 0.22). Individuals who received the brochure were more likely to initiate the online screener than those who received a postcard (P = 0.01). In Study 2, of those who completed the telephone screening, 60.9 % of men (n = 23) had received the targeted postcard as compared to the generic postcard (39.1 %, P = 0.30). The reverse was true for women (n = 62, 38.7 vs. 61.3 %, P = 0.08).

conclusionsThese studies suggest there was little difference in the reach of postcards versus brochures. However, recipients of brochures were more likely to continue to the next stage of study participation. As expected, men's response to the weight gain prevention messages was lower than women's response; but using targeted messages appears to have modestly increased the proportion of male respondents. These studies add to the limited experimental literature on recruitment messaging and provide further indication for using targeted messages to reach underrepresented populations while providing initial evidence on the effect of mailing type on message reach.

trial registrationThe Study of Novel Approaches to Weight Gain Prevention was registered with ClinicalTrials.gov (identifier: NCT01183689 ) on 13 August 2010.

Indexed as

Patient SelectionWeight GainAdultFemaleHumansMaleObesityPostal ServiceResearch DesignSex CharacteristicsTelephoneYoung AdultMenRecruitmentWeight gain preventionYoung adults

Identifiers

PMID27278474
PMCPMC4897900

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.