Evidence map›Paper›PMID 27278056›Full record

ArticleJournal of children's orthopaedics2016

Does radiofrequency ablation (RFA) epiphysiodesis affect adjacent joint cartilage?

Juan Manuel Shiguetomi-Medina, O Rahbek, A A H Abood, H Stødkilde-Jørgensen, J L Ramírez Garcia-Luna, B Møller-Madsen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of children's orthopaedics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Guided growth: mechanism and reversibility of modulation.Journal of children's orthopaedics · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Juan Manuel Shiguetomi-MedinaOrthopaedic Research Laboratory, Danish Paediatric Orthopaedic Research, Aarhus University Hospital NBG, Aarhus University, Noerrebrogade 44 Building 1A, 8000, Aarhus C, Denmark. jmshigue@gmail.com.
O RahbekDepartment of Children's Orthopaedics, Aarhus University Hospital NBG, Noerrebrogade 44, 8000, Aarhus C, Denmark.
A A H AboodOrthopaedic Research Laboratory, Danish Paediatric Orthopaedic Research, Aarhus University Hospital NBG, Aarhus University, Noerrebrogade 44 Building 1A, 8000, Aarhus C, Denmark.
H Stødkilde-JørgensenThe MR Research Center, Aarhus University Hospital, Skejby, Brendstrupgårdsvej 100, 8200, Aarhus N, Denmark.
J L Ramírez Garcia-LunaDepartment of Clinical Epidemiology and Public Health, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Venustiano Carranza 2045, 78210, San Luis Potosí, SLP, Mexico.
B Møller-MadsenOrthopaedic Research Laboratory, Danish Paediatric Orthopaedic Research, Aarhus University Hospital NBG, Aarhus University, Noerrebrogade 44 Building 1A, 8000, Aarhus C, Denmark.
Aarhus University Hospital · DKAutonomous University of San Luis Potosí · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo test the hypothesis that epiphysiodesis made with radiofrequency ablation (RFA) is a safe procedure that disrupts the growth plate without damaging the adjacent joint articular cartilage.

methodsRFA epiphysiodesis was done during 8 min in vivo in 40 growing pig tibia physis. In addition, three tibiae were ablated for 16 min and three more for 24 min. As a burned cartilage reference, six tibiae were ablated on the joint articular cartilage for 8 min. After the procedure, the animals were terminated and the tibiae were harvested. Magnetic resonance imaging (MRI) was done ex vivo to evaluate the joint articular cartilage in all samples. We used T1-weighted, T2-weighted, and water content sequences under a 1.5 T magnetic field.

resultsOn the burned articular cartilage, intensity changes were observed at MRI. We found no evidence of articular cartilage damage on the 40 8-min RFA procedures. The tibiae ablated for 16 min and 24 min showed intact joint cartilage.

conclusionsEpiphysiodesis using RFA is safe for the adjacent articular cartilage. This study shows that RFA can be done safely in the growing physis of pigs, even with triple duration procedures.

Indexed as

Cartilage damageEpiphysiodesisMRIRFA

Identifiers

PMID27278056
PMCPMC4940242
OpenAlexW2415691082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.