Evidence map›Paper›PMID 27278024›Full record

ArticleJournal of medical ultrasonics (2001)2014

Evaluation of whether the ultrasonographic onion skin sign is specific for the diagnosis of an appendiceal mucocele.

Toru Kameda, Fukiko Kawai, Nobuyuki Taniguchi, Kiyoka Omoto, Yasuyuki Kobori, Kazukiyo Arakawa

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Journal of medical ultrasonics (2001), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A general overview of mucocele of appendix.Journal of family medicine and primary care · 2020
    Review
  7. Article
  8. Article
  9. Three Cases of Appendiceal Mucocele: From Diagnosis to Management.Saudi journal of medicine & medical sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Toru KamedaDepartment of Ultrasound Medicine, Saiseikai Utsunomiya Hospital, 911-1 Takebayashi, Utsunomiya, Tochigi, 321-0974, Japan. kamekame@pb3.so-net.ne.jp.
Fukiko KawaiDepartment of Ultrasound Medicine, Saiseikai Utsunomiya Hospital, 911-1 Takebayashi, Utsunomiya, Tochigi, 321-0974, Japan.
Nobuyuki TaniguchiDepartment of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke, Japan.
Kiyoka OmotoDepartment of Laboratory Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Yasuyuki KoboriDepartment of Clinical Laboratory, Saiseikai Utsunomiya Hospital, Utsunomiya, Japan.
Kazukiyo ArakawaDepartment of Radiology, Saiseikai Utsunomiya Hospital, Utsunomiya, Japan.
Saiseikai Utsunomiya hospital · JPJichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate whether the onion skin sign on ultrasonography (US) of the lower abdomen is specific for the diagnosis of an appendiceal mucocele.

methodsOur study included 231 lesions from 229 patients in whom transabdominal US detected lesions in the lower abdomen and who had definitive pathological diagnoses in the small bowel, ileocecal valve, cecum, appendix, mesentery, adnexa uteri or pelvic cavity outside the major organs. Patients with metastatic tumors were excluded. We reviewed the reports and images from transabdominal US and checked for the presence of the onion skin sign. The sensitivity, specificity, and accuracy of the sign for the diagnosis of an appendiceal mucocele were calculated.

resultsFive (2.2 %) of the 231 lesions showed the onion skin sign on US and all were diagnosed with an appendiceal mucocele. The sensitivity, specificity, and accuracy of the sign for the diagnosis of an appendiceal mucocele were 63, 100, and 99 %, respectively.

conclusionsThe onion skin sign in the lower abdomen appears to be specific for the diagnosis of an appendiceal mucocele. In cases where the onion skin sign is obviously present in the lower abdomen on US, an appendiceal mucocele should be considered as the leading diagnosis.

Indexed as

UltrasonographyAdolescentAdultAgedAged, 80 and overAppendixCecal DiseasesChildDiagnosis, DifferentialFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedMucoceleSensitivity and SpecificityAppendixMucoceleOnion skin signUltrasonography

Identifiers

PMID27278024
OpenAlexW2044869850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.