ArticleScientific reports2016
The structural alteration of gut microbiota in low-birth-weight mice undergoing accelerated postnatal growth.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- A maternal effect shapes early-life adaptive body size variation in house mice.bioRxiv : the preprint server for biology · 2026Article
- Generalized Ketogenic Diet Induced Liver Impairment and Reduced Probiotics Abundance of Gut Microbiota in Rat.Biology · 2024Article
- Associations between maternal microbiome, metabolome and incidence of low-birth weight in Guatemalan participants from the Women First Trial.Frontiers in microbiology · 2024Article
- Timely Control of Gastrointestinal Eubiosis: A Strategic Pillar of Pig Health.Microorganisms · 2021Review
- The composition of the human fecal microbiota might be significantly associated with fecal SCFA levels under hyperbaric conditions.Bioscience of microbiota, food and health · 2021Article
- Review
- Prevention of excessive exercise-induced adverse effects in rats with Bacillus subtilis BSB3.Journal of applied microbiology · 2020Article
- Changes in Faecal Microbiota Profiles Associated With Performance and Birthweight of Piglets.Frontiers in microbiology · 2020Article
- Maternal imprinting of the neonatal microbiota colonization in intrauterine growth restricted piglets: a review.Journal of animal science and biotechnology · 2019Review
- Maternal Genistein Intake Mitigates the Deleterious Effects of High-Fat Diet on Glucose and Lipid Metabolism and Modulates Gut Microbiota in Adult Life of Male Mice.Frontiers in physiology · 2019Article
- Core Gut Bacteria Analysis of Healthy Mice.Frontiers in microbiology · 2019Article
- Characterization of the Early Life Microbiota Development and PredominantFrontiers in microbiology · 2019Article
- Impacts of Diet and Exercise on Maternal Gut Microbiota Are Transferred to Offspring.Frontiers in endocrinology · 2018Article
- Differences in the Gut Microbiota Establishment and Metabolome Characteristics Between Low- and Normal-Birth-Weight Piglets During Early-Life.Frontiers in microbiology · 2018Article
- Microbiota composition of simultaneously colonized mice housed under either a gnotobiotic isolator or individually ventilated cage regime.Scientific reports · 2017Article
- Intestinal Microbiota and Weight-Gain in Preterm Neonates.Frontiers in microbiology · 2017Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The transient disruption of gut microbiota in infancy by antibiotics causes adult adiposity in mice. Accelerated postnatal growth (A) leads to a higher risk of adult metabolic syndrome in low birth-weight (LB) humans than in normal birth-weight (NB) individuals, but the underlying mechanism remains unclear. Here, we set up an experiment using LB + A mice, NB + A mice, and control mice with NB and normal postnatal growth. At 24 weeks of age (adulthood), while NB + A animals had a normal body fat content and glucose tolerance compared with controls, LB + A mice exhibited excessive adiposity and glucose intolerance. In infancy, more fecal bacteria implicated in obesity were increased in LB + A pups than in NB + A pups, including Desulfovibrionaceae, Enterorhabdus, and Barnesiella. One bacterium from the Lactobacillus genus, which has been implicated in prevention of adult adiposity, was enhanced only in NB + A pups. Besides, LB + A pups, but not NB + A pups, showed disrupted gut microbiota fermentation activity. After weaning, the fecal microbiota composition of LB + A mice, but not that of NB + A animals, became similar to that of controls by 24 weeks. In infancy, LB + A mice have a more dysbiotic gut microbiome compared to NB + A mice, which might increase their risk of adult metabolic syndrome.
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