Evidence map›Paper›PMID 27277259›Full record

ArticleEuropean radiology2017

Assessing pediatric ileocolonic Crohn's disease activity based on global MR enterography scores.

Fabio Pomerri, Faise Al Bunni, Monica Zuliani, Graziella Guariso, Marco Gasparetto, Benedetta Giorgi, Mara Cananzi, Pier Carlo Muzzio

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In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Correlation between magnetic resonance enterography and ileo-colonoscopy for assessment of disease activity in terminal ileal Crohn's disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabio PomerriDepartment of Medicine-DIMED, University of Padova, Via Giustiniani 2, 35128, Padova, Italy. fabio.pomerri@unipd.it.
Faise Al BunniRadiology Unit, S. Maria della Misericordia, Rovigo Hospital, Rovigo, Italy.
Monica ZulianiDepartment of Medicine-DIMED, University of Padova, Via Giustiniani 2, 35128, Padova, Italy.
Graziella GuarisoDepartment of Women and Child Health, University of Padova, Padova, Italy.
Marco GasparettoDepartment of Women and Child Health, University of Padova, Padova, Italy.
Benedetta GiorgiDepartment of Medicine-DIMED, University of Padova, Via Giustiniani 2, 35128, Padova, Italy.
Mara CananziDepartment of Women and Child Health, University of Padova, Padova, Italy.
Pier Carlo MuzzioDepartment of Medicine-DIMED, University of Padova, Via Giustiniani 2, 35128, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study was aimed at correlating a magnetic resonance index of activity (MaRIA) and a magnetic resonance enterography global score (MEGS) with activity indexes in a paediatric population with Crohn's disease (CD).

methodsThis retrospective study included 32 paediatric patients (median age 14.5 years, 18 male) with proven CD who underwent magnetic resonance enterography (MRE). A correlation analysis was performed on the MRE-based scores, the simplified endoscopic score for CD (SES-CD), the paediatric Crohn's disease activity index (PCDAI), and C-reactive protein (CRP) levels. Based on PCDAI, comparison of both global MaRIA and MEGS was made between patients with mild and moderate/severe disease activity.

resultsGlobal MaRIA correlated with SES-CD (r = 0.70, p = 0.001) and PCDAI (r = 0.42, p = 0.016). MEGS correlated with PCDAI (r = 0.46, p = 0.007) and CRP levels (r = 0.35, p = 0.046). MEGS differed significantly (p = 0.027) between patients grouped by clinical disease severity.

conclusionsMRE-based global scores correlated with clinical indexes of CD activity. Therefore, they represent a potential useful tool to predict CD activity and severity, as well as a possible promising alternative to endoscopy, to monitor paediatric patients with CD during their follow-up. KEY POINTS: • MRE is widely used to for accurate assessment of CD. • Global MaRIA and MEGS have been suggested as indicators of CD activity. • Paediatric studies comparing MRE-based global scores with clinical CD activity are lacking. • Such scores can serve as predictors of CD activity/severity in paediatric patients. • MRE offers an alternative to clinical score/endoscopy for paediatric CD monitoring.

Indexed as

AdolescentAdultChildColonCrohn DiseaseFemaleHumansIleumMagnetic Resonance ImagingMaleReproducibility of ResultsRetrospective StudiesSeverity of Illness IndexYoung AdultCrohn’s diseaseDisease activityDisease severityMagnetic resonance enterographyPaediatrics

Identifiers

PMID27277259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.