Evidence map›Paper›PMID 27276911›Full record

ReviewApplied microbiology and biotechnology2016

Enzymatic synthesis of bioactive compounds with high potential for cosmeceutical application.

Io Antonopoulou, Simona Varriale, Evangelos Topakas, Ulrika Rova, Paul Christakopoulos, Vincenza Faraco

Open access · hybridAbstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 94 citations in OpenAlex.

  1. Trial
  2. Ethnomedicinal Uses of Thai Legumes (Food science & nutrition · 2026
    Review
  3. Review
  4. Article
  5. Anti-ageing activities of nanovesicles derived fromJournal of extracellular biology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Molecules (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Io AntonopoulouDivision of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 97187, Luleå, Sweden.
Simona VarrialeDepartment of Chemical Sciences, University of Naples "Federico II", Naples, Italy.
Evangelos TopakasBiotechnology Laboratory, School of Chemical Engineering, National Technical University of Athens, 15700, Athens, Greece.
Ulrika RovaDivision of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 97187, Luleå, Sweden.
Paul ChristakopoulosDivision of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 97187, Luleå, Sweden.
Vincenza FaracoDepartment of Chemical Sciences, University of Naples "Federico II", Naples, Italy. vfaraco@unina.it.
Luleå University of Technology · SEUniversity of Naples Federico II · ITNational Technical University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cosmeceuticals are cosmetic products containing biologically active ingredients purporting to offer a pharmaceutical therapeutic benefit. The active ingredients can be extracted and purified from natural sources (botanicals, herbal extracts, or animals) but can also be obtained biotechnologically by fermentation and cell cultures or by enzymatic synthesis and modification of natural compounds. A cosmeceutical ingredient should possess an attractive property such as anti-oxidant, anti-inflammatory, skin whitening, anti-aging, anti-wrinkling, or photoprotective activity, among others. During the past years, there has been an increased interest on the enzymatic synthesis of bioactive esters and glycosides based on (trans)esterification, (trans)glycosylation, or oxidation reactions. Natural bioactive compounds with exceptional theurapeutic properties and low toxicity may offer a new insight into the design and development of potent and beneficial cosmetics. This review gives an overview of the enzymatic modifications which are performed currently for the synthesis of products with attractive properties for the cosmeceutical industry.

Indexed as

BacteriaCosmeceuticalsCosmeticsEstersFungiGlycosidesSkinCosmeceuticalsCosmeticsEstersGlycosidesAnti-agingAnti-inflammatoryAnti-microbialAnti-oxidantAnti-wrinklingBacterialFeruloyl esterasesFungalGlycosidasesLaccasesLipasesPhotoprotectiveProteasesSkin whiteningTannasesTransferases

Identifiers

PMID27276911
PMCPMC4939304
OpenAlexW2415531596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.