Evidence map›Paper›PMID 27276875›Full record

ArticleBMC complementary and alternative medicine2016

Characteristics of traditional Chinese medicine users and prescription analysis for pediatric atopic dermatitis: a population-based study.

Yu-Chun Chen, Yi-Hsuan Lin, Sindy Hu, Hsing-Yu Chen

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Traditional Chinese Medicine for Pediatric Allergic Diseases.Current allergy and asthma reports · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Effectiveness and Safety of Herbal Medicine for Atopic Dermatitis: An Overview of Systematic Reviews.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Characteristics of Traditional Chinese Medicine Use in Pediatric Dislocations, Sprains and Strains.International journal of environmental research and public health · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yu-Chun ChenDepartment of Medical Research and Education, National Yang-Ming University Hospital, I-Lan, Taiwan.
Yi-Hsuan LinDivision of Chinese Internal Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu Rd., Gueishan Dist., Taoyuan City, 33378, Taiwan.
Sindy HuSchool of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Hsing-Yu ChenDivision of Chinese Internal Medicine, Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, No. 123, Dinghu Rd., Gueishan Dist., Taoyuan City, 33378, Taiwan. b8705016@gmail.com.
Chang Gung Memorial Hospital · TWChang Gung University · TWNational Yang Ming University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtopic dermatitis among children is an important issue due to relapses and skin manifestations. Traditional Chinese medicine (TCM) is commonly used to treat children with atopic dermatitis. The aim of this study was to investigate the characteristics and TCM prescriptions of patients with atopic dermatitis using a nationwide database.

methodsChildren younger than 12 years of age diagnosed with atopic dermatitis, defined as ICD-9-CM codes 691.8 and 692.x, were identified from the database. Data on age, diagnosis codes, area of residence and use of corticosteroids of the TCM users were recorded. Association rule mining was used to analyze the prescriptions used for atopic dermatitis.

resultsWe identified 13,646 children with atopic dermatitis using TCM in 2007. Female gender (OR: 0.83 for male gender), adolescence (OR: 10.0, 95 % CI: 8.88-11.15) and allergic rhinitis (OR: 2.44, 95 % CI: 2.10-2.85) were associated with the use of TCM. Fewer of the TCM users were prescribed with corticosteroids (35.8 % of all TCM users), but the TCM users had a higher rate of long-term topical corticosteroid therapy (10.6 % for TCM users versus 2.0 % for those who did not use TCM). Chinese herbal medicine (CHM) was used by 93.7 % of all TCM users in 36,398 prescriptions. On average, 5.6 kinds of CHM were used in combination. The relationship between the CHMs constituted a network, in which Xiao-Feng-San was the core treatment for atopic dermatitis.

conclusionsIn this study, we described the characteristics of children with atopic dermatitis who use TCM in Taiwan. and identified the core CHM treatment. Further research on the safety and efficacy of this treatment are still needed.

Indexed as

Medicine, Chinese TraditionalAdrenal Cortex HormonesChildChild, PreschoolDermatitis, AtopicDrug PrescriptionsDrugs, Chinese HerbalFemaleHumansInfantMaleTaiwanAdrenal Cortex HormonesDrugs, Chinese HerbalAtopic dermatitisChinese herbal medicinePediatricsTraditional Chinese medicine

Identifiers

PMID27276875
PMCPMC4898376
OpenAlexW2414238981

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.