Evidence map›Paper›PMID 27276432›Full record

Observational studyJournal of pediatric gastroenterology and nutrition2017

Propofol Use in Pediatric Patients With Food Allergy and Eosinophilic Esophagitis.

Pooja Mehta, Shikha S Sundaram, Glenn T Furuta, Zhaoxing Pan, Dan Atkins, Scott Markowitz

Erratum issuedOpen access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of pediatric gastroenterology and nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Progression of systemic lupus erythematosus associated with propofol administration: a case report.European journal of hospital pharmacy : science and practice · 2018
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pooja Mehta*Digestive Health Institute †Gastrointestinal Eosinophilic Diseases Program, Digestive Health Institute ‡Department of Biostatistics §Gastrointestinal Eosinophilic Diseases Program, Section of Allergy and Immunology ¶Department of Anesthesiology, Children's Hospital Colorado, University of Colorado, School of Medicine, Aurora, CO.
Shikha S Sundaram
Glenn T Furuta
Zhaoxing Pan
Dan Atkins
Scott Markowitz
University of Colorado Denver · US

Funding

TRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI GLENN T FURUTA, Marc E. Rothenberg · 2014 to 2026
$18.5M
Institutional Training Grant in Pediatric GastroenterologyT32DK067009 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI RONALD J. SOKOL, Edwin Fulco de Zoeten · 2005 to 2026
$7.1M
Patient research in eosinophilic gastrointestinal diseasesK24DK100303 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI FURUTA, GLENN T · 2013 to 2017
$889k
NIAID NIH HHS U54 AI117804NIDDK NIH HHS K24 DK100303NIDDK NIH HHS T32 DK067009
6 · The paper itself

Abstract

Propofol is a safe, well-tolerated anesthetic that is labeled as contraindicated in patients with egg or soy allergy. This contraindication has become increasingly problematic given the rising incidence of food allergy and eosinophilic esophagitis (EoE). To address this issue, we studied practice patterns of propofol use for esophagogastroduodenoscopies in children with EoE and food allergies at our institution. A retrospective observational study of 1365 esophagogastroduodenoscopies from January 2013 to June 2014 was performed. Data were analyzed using Student t tests, chi square tests, Fisher exact tests, and multivariable logistic regression. We found that propofol was used significantly less in patients with egg or soy allergy, and in patients with EoE, even after adjusting for the presence of food allergy. There was no difference in complication rates relative to propofol use. Propofol was used safely in pediatric patients with EoE and food allergy in this limited single-center review.

Indexed as

Anesthetics, IntravenousEndoscopy, Digestive SystemEosinophilic EsophagitisFood HypersensitivityPropofolAdolescentChildChild, PreschoolColoradoContraindications, DrugFemaleHumansInfantInfant, NewbornMalePractice Patterns, Physicians'Anesthetics, IntravenousPropofol

Identifiers

PMID27276432
PMCPMC5145772
OpenAlexW2410444921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.