Evidence map›Paper›PMID 27275812›Full record

ReviewObstetrics and gynecology2016

Opioid Use Disorder in Pregnancy: Health Policy and Practice in the Midst of an Epidemic.

Elizabeth E Krans, Stephen W Patrick

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Obstetrics and gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03175653 (Assessing the Impact of the Number of Opiates Prescribed on Post Cesarean Pain Control), which is not on this map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
48.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03175653 nawithdrawnnot on this mapstarted 2017, after this paper: background citation

Assessing the Impact of the Number of Opiates Prescribed on Post Cesarean Pain Control: A Randomized Controlled Trial

TypeinterventionalSponsorMount Carmel Health SystemRan2017 to 2020Enrolled0ConditionsPost-operative Pain ControlArmsOxycodone Pill A, Oxycodone Pill B
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it, 194 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Trends in prenatal prescription opioid use among Medicaid beneficiaries in Wisconsin, 2010-2019.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  15. Informing evidence-based medicine for opioid use disorder using pharmacoeconomic studies.Expert review of pharmacoeconomics & outcomes research · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elizabeth E KransDepartment of Obstetrics, Gynecology & Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania; and the Departments of Pediatrics and Health Policy, Vanderbilt University, Nashville, Tennessee.
Stephen W Patrick
Magee-Womens Research Institute · US

Funding

University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
Neonatal Abstinence Syndrome: Risk of Drug Withdrawal in Opioid-Exposed InfantsK23DA038720 · NIDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PATRICK, STEPHEN W · 2015 to 2019
$844k
NCATS NIH HHS KL2 TR000146NIDA NIH HHS K23 DA038720
6 · The paper itself

Abstract

Opioid abuse among pregnant women has reached epidemic proportions and has influenced maternal and child health policy at the federal, state, and local levels. As a result, we review the current state of opioid use in pregnancy and evaluate recent legislative and health policy initiatives designed to combat opioid addiction in pregnancy. We emphasize the importance of safe and responsible opioid-prescribing practices, expanding the availability and accessibility of medication-assisted treatment and standardizing care for neonates at risk of neonatal abstinence syndrome. Efforts to penalize pregnant women and negative consequences for disclosing substance use to health care providers are harmful and may prevent women from seeking prenatal care and other beneficial health care services during pregnancy. Instead, health care providers should advocate for health policy informed by scientific research and evidence-based practice to reduce the burden of prenatal opioid abuse and optimize outcomes for mothers and their neonates.

Indexed as

Health PolicyNeonatal Abstinence SyndromeOpioid-Related DisordersPerinatal CareFemaleHumansInfant, NewbornPregnancyPregnancy ComplicationsQuality Improvement

Identifiers

PMID27275812
PMCPMC4917415
OpenAlexW2414636183

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.