Evidence map›Paper›PMID 27275625›Full record

ArticleLiver international : official journal of the International Association for the Study of the Liver2017

The prevalence of hepatitis C virus infection in Egypt 2015: implications for future policy on prevention and treatment.

Amr Kandeel, Mohamad Genedy, Samir El-Refai, Anna L Funk, Arnaud Fontanet, Maha Talaat

3 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Liver international : official journal of the International Association for the Study of the Liver, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 74 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 4 pooled it
24.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03254901 unknown statusnot on this mapstarted 2018, after this paper: background citation

Detection of Hepatitis C Infection by Oraquick Test Among Health Care Workers in Assiut Governorate and Treatment Outcome Among True Positive Cases

TypeobservationalSponsorAssiut UniversityRan2018 to 2018Enrolled1,200ConditionsHepatitis CArmsScreening test by Oraquick test
NCT03341988 phase1completednot on this map

Evaluation of the Clinical Effects of Ombitasvir/Paritaprevir/Ritonavir Regimen in the Treatment of Chronic HCV Patients in CKD Versus ESRD Patients in Assiut University Hospital

TypeinterventionalSponsorAssiut UniversityRan2017 to 2018Enrolled100ConditionsHepatitis CArmsOmbitasvir-Paritaprevir-Ritonavir Tab 12.5-75-50 milligram
NCT03894696 unknown statusnot on this mapstarted 2019, after this paper: background citation

Frequency of Anxiety and Depression in Chronic Hepatitis C Patients Recieving Direct-Acting Antiviral Agents.

TypeobservationalSponsorAssiut UniversityRan2019 to 2020Enrolled200ConditionsChronic Hepatitis cArmsDirect Acting Antivirals
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 4 syntheses or guidelines pooled it, 280 citations in OpenAlex.

  1. Pooled it
  2. Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021
    Pooled it
  3. Hepatocellular Carcinoma (HCC) in Egypt: A comprehensive overview.Journal of the Egyptian National Cancer Institute · 2020
    Pooled it
  4. Pooled it
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  13. Outcome of laparotomy and conservative treatment of patients with acute mesenteric venous ischemia with viable bowel.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  14. Article
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  17. Tropical medicine and infectious disease · 2022
    Article
  18. Article
  19. Review
  20. Pathogens and global health · 2022
    Observational

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Amr KandeelMinistry of Health and Population, Cairo, Egypt.
Mohamad GenedyMinistry of Health and Population, Cairo, Egypt.
Samir El-RefaiMinistry of Health and Population, Cairo, Egypt.
Anna L FunkInstitut Pasteur, Paris, France.
Arnaud FontanetInstitut Pasteur, Paris, France.
Maha TalaatGlobal Disease Detection Regional Center, US Centers for Disease Control and Prevention, Cairo, Egypt.
Ministry of Health and Population · EGInstitut Pasteur · FRUnited States Naval Medical Research Unit III · EG

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

BACKGROUND &

aimsIn 2015, a national Egyptian health issue survey was conducted to describe the prevalence of hepatitis C virus (HCV) infection. In this paper, we describe the HCV burden in 2015, compare the results with the national survey conducted in 2008, and discuss the implications of the new findings on prevention of HCV in Egypt.

methodsA multistage probability sampling approach was used, similar to the national demographic survey conducted in 2008. More than 90% of sampled individuals complied with the interview and provided blood samples.

resultsIn the 15-59-year age groups, the prevalence of HCV antibody was found to be 10.0% (95% CI 9.5-10.5) and that of HCV RNA to be 7.0% (95% CI 6.6-7.4). In children, 1-14 years old, the prevalence of HCV antibody and HCV RNA were 0.4% (95% CI 0.3-0.5) and 0.2% (95% CI 0.1-0.3) respectively. Approximately, 3.7 million persons have chronic HCV infection in the age group 15-59 in 2015. An estimated 29% reduction in HCV RNA prevalence has been seen since 2008, which is largely attributable to the ageing of the group infected 40-50 years ago during the mass schistosomiasis treatment campaigns. Prevention efforts may have also contributed to this decline, with an estimated 75% (95% CI 6-45) decrease in HCV incidence in the 0-19 year age groups over the past 20 years.

conclusionsThese findings can be used to shape future HCV prevention policies in Egypt.

Indexed as

AdolescentAdultAge DistributionEgyptFemaleHealth SurveysHepacivirusHepatitis CHepatitis C AntibodiesHumansIncidenceMaleMiddle AgedRisk FactorsRNA, ViralSex DistributionHepatitis C AntibodiesRNA, Viralhepatitis C Egyptincidence HCVnation-wide surveysprevalence HCV

Identifiers

PMID27275625
PMCPMC5145777
OpenAlexW2410976255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.